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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: Differences in lipid metabolism in acquired versus preexisting glucose intolerance during gestation: role of free fatty acids and sphingosine-1-phosphate

Fig. 7

Opposite shifts in the sphingolipids during gestation. Relative (normalized to 100 mg hepatic tissue) and absolute (normalized to whole liver weight) A, B sphingomyelin and C, D sphingosine-1-phosphate (S1P) of mice with preexisting impaired glucose tolerance (preIGT), impaired glucose tolerance acquired during gestation (aqIGT), and NMRI mice, at time points preconceptional (pc.; white bars) and day 14.5 of gestation (d14.5; black bars). Data are presented as means ± SEM (A and B n = 12–15, C and D n = 6 animals per group). *p < 0.05, **p < 0.01, ***p < 0.001, NMRI pc. vs preIGT pc.: 1p < 0.05; preIGT d14.5 vs. aqIGT d14.5: 2p < 0.001; preIGT pc. vs. aqIGT pc.: 3p < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X