Table 4 AUC values and cutoff values of indicators for the diagnosis of STSL
From: Clinical characteristics of sitosterolemic children with xanthomas as the first manifestation
|  | AUC values (95% CI) | p value of AUC | Maximum of Youden’s J statistic | Cutoff values for the diagnosis of STSL | ||
|---|---|---|---|---|---|---|
Cutoff value | Sensitivity | Specificity | ||||
Chol | 0.910 (0.751-1.000) | 0.005 | 0.9 | ≤ 15.41 mmol/L | 0.9 | 1.0 |
LDL-c | 0.886 (0.712-1.000) | 0.008 | 0.8 | ≤ 13.22 mmol/L | 0.8 | 1.0 |
MPV | 0.869 (0.704-1.000) | 0.009 | 0.6 | ≥ 9.05 fl. | 1.0 | 0.6 |
Hb | 0.879 (0.700-1.000) | 0.010 | 0.8 | ≤ 120 g/L | 0.8 | 0.9 |
Paternal Chol | 0.857(0.677-1.000) | 0.015 | 0.7 | ≤ 7.25 mmol/L | 0.8 | 0.9 |
Paternal LDL-c | 0.814(0.597-1.000) | 0.032 | 0.7 | ≤ 5.02 mmol/L | 0.8 | 0.9 |
Maternal Chol | 0.914(0.776-1.000) | 0.005 | 0.7 | ≤ 5.25 mmol/L | 1.0 | 0.7 |
Maternal LDL-c | 0.971(0.901-1.000) | 0.001 | 0.9 | ≤ 3.43 mmol/L | 1.0 | 0.9 |