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Table 6 The best threshold, sensitivities, specificities, and area under the curve of lipid-related parameters for the screening of NAFLD in different BMI groups

From: Utility of traditional and non-traditional lipid indicators in the diagnosis of nonalcoholic fatty liver disease in a Japanese population

 

AUC

95%CI low

95%CI upp

Best threshold

Specificity

Sensitivity

Low weight (BMI < 18.5 kg/m2)

      

TC

0.85

0.66

1.00

5.11

0.65

1.00

HDL-C

0.63

0.12

1.00

2.18

0.87

0.67

LDL-C

0.86

0.83

0.89

3.27

0.84

1.00

TG

0.93

0.89

0.97

0.88

0.89

1.00

Non-HDL-C

0.88

0.84

0.92

3.85

0.85

1.00

RC

0.93

0.89

0.97

0.59

0.90

1.00

TC/HDL-C ratio

0.66

0.39

0.93

2.81

0.52

1.00

TG/HDL-C ratio

0.86

0.79

0.93

0.48

0.81

1.00

LDL-C/HDL-C ratio

0.64

0.35

0.93

1.51

0.48

1.00

Non-HDL-C/HDL-C ratio

0.66

0.39

0.93

1.81

0.52

1.00

RC/HDL-C ratio

0.78

0.61

0.94

0.29

0.68

1.00

Normal weight (BMI:18.5–24.9 kg/m2)

TC

0.62

0.60

0.63

5.16

0.57

0.62

HDL-C

0.72

0.71

0.73

1.40

0.57

0.76

LDL-C

0.67

0.66

0.69

3.04

0.54

0.72

TG

0.77

0.76

0.78

0.84

0.68

0.73

Non-HDL-C

0.70

0.69

0.72

3.77

0.63

0.68

RC

0.77

0.75

0.78

0.56

0.63

0.78

TC/HDL-C ratio

0.76

0.75

0.78

3.80

0.67

0.75

TG/HDL-C ratio

0.78

0.77

0.80

0.60

0.67

0.76

LDL-C/HDL-C ratio

0.75

0.74

0.77

2.30

0.64

0.77

Non-HDL-C/HDL-C ratio

0.76

0.75

0.78

2.80

0.67

0.75

RC/HDL-C ratio

0.78

0.77

0.80

0.40

0.64

0.80

Overweight/Obese (BMI ≥ 25 kg/m2)

TC

0.57

0.55

0.60

5.52

0.65

0.47

HDL-C

0.64

0.61

0.66

1.22

0.54

0.69

LDL-C

0.59

0.56

0.61

3.62

0.68

0.47

TG

0.68

0.66

0.70

1.24

0.71

0.56

Non-HDL-C

0.62

0.60

0.64

4.00

0.53

0.66

RC

0.68

0.66

0.70

0.73

0.73

0.53

TC/HDL-C ratio

0.67

0.64

0.69

4.59

0.64

0.62

TG/HDL-C ratio

0.69

0.67

0.71

0.96

0.64

0.65

LDL-C/HDL-C ratio

0.65

0.63

0.68

2.75

0.55

0.70

Non-HDL-C/HDL-C ratio

0.67

0.64

0.69

3.59

0.64

0.62

RC/HDL-C ratio

0.69

0.67

0.71

0.57

0.61

0.67

  1. Abbreviations: AUC: area under the curve; other abbreviations as in Table ​1