New insight into the role of lipid metabolism-related proteins in rheumatic heart valve disease

Table 3 The relevant mRNA expression level of lipid metabolism related genes and inflammatory factor

	ACAT1	ABCA1	TNF-α	IL-10	MCP1	CD68
Ischemic mitral valve(n = 4)	1.00	1.00	1.00	1.00	1.00	1.00
Rheumatic mitral valve-1(n = 10)	1.86 ± 0.16^★	33.3 ± 3.69^★	3.41 ± 0.30^★	4.78 ± 0.41^★	2.60 ± 0.23^★	2.27 ± 0.36^★
Rheumatic mitral valve-2(n = 10)	1.42 ± 0.12^★#	22.1 ± 2.30^★#	5.11 ± 0.40^★#	6.32 ± 053^★#	3.45 ± 0.34^★#	3.40 ± 0.26^★#

ACAT1 acetoacetyl Coenzyme A thiolase − 1, ABCA1 ATP binding cassette subfamily A member 1, TNFα tumour necrosis factor α, IL10 interleukin10, MCP methyl cyclopentenolone
^★there was significant difference between three groups (P < 0.05)
^#there was significant difference between Rheumatic mitral valve-1and Rheumatic mitral valve-2 (P < 0.05)

ISSN: 1476-511X