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Fig. 9 | Lipids in Health and Disease

Fig. 9

From: WY-14643 attenuates lipid deposition via activation of the PPARα/CPT1A axis by targeting Gly335 to inhibit cell proliferation and migration in ccRCC

Fig. 9

The highest ranked position of WY-14,643 docking the PPARα protein complex. a. Interactions between WY-14,643 and the activating residues of PPARα in a 2D model. b. Interactions between WY-14,643 and PPARα are delineated in a 3D model. Hydrogen bonds are indicated by red dashed lines, and the docked amino acid residue is also highlighted

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Lipids in Health and Disease

ISSN: 1476-511X