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Table 1 Clinical characteristics of HUA patients with and without CAD

From: Serum growth differentiation factor-15 and non-esterified fatty acid levels in patients with coronary artery disease and hyperuricemia

Characteristics

HUA without CAD (n = 191)

HUA with CAD (n = 159)

P value

Clinical variables

 Age (year)

57 (52, 63)

59 (52, 67)

0.061

 Diabetes Mellitus n (%)

21 (11.0%)

24 (15.1%)

0.254

 Hypertension n(%)

59 (30.9%)

58 (36.5%)

0.270

 Smoking n(%)

23 (12.0%)

23 (14.4%)

0.504

 Alcohol consumption n(%)

16 (8.3%)

14 (8.8%)

0.887

 SBP (mmHg)

131 (122, 145)

131 (123, 145)

0.639

 DBP (mmHg)

85 (77, 96)

85 (77, 95)

0.850

 Gensinin scores

3.0 (1.50, 3.50)

36.0(26.0, 62.0)

 < 0.001

Laboratory variables

 Urea(mmol/L)

5.82 (4.74, 6.79)

6.20 (5.10, 8.25)

0.003

 Cr (μmol/L)

79.0 (70.0, 92.0)

86.0 (74.0, 102.0)

0.002

 UA (μmol/L)

504.0 (466.0, 536.5)

516 (486.0, 563.0)

 < 0.001

 FPG (mmol/L)

5.09 (4.61, 5.59)

5.00 (4.52, 5.90)

0.786

 TC (mmol/L)

4.21 ± 0.05

4.52 ± 0.07

 < 0.001

 TG (mmol/L)

1.62 (1.05, 2.31)

1.85 (1.24, 2.47)

0.025

 HDL-c (mmol/L)

0.97 (0.84, 1.10)

0.88 (0.76, 1.02)

 < 0.001

 LDL-c (mmol/L)

2.02 (1.55, 2.56)

2.31 (1.78, 2.83)

0.001

 NEFA(mmol/L)

0.32 (0.24, 0.40)

0.45 (0.32, 0.60)

 < 0.001

 GDF-15(pg/dL)

5.78 (4.58, 8.57)

8.48 (6.67, 12.73)

 < 0.001

  1. SBP systolic blood pressure, DBP diastolic blood pressure, Cr creatinine, UA uric acid, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, HDL-c high density lipoprotein cholesterol, LDL-c low density lipoprotein cholesterol, NEFA non-esterified fatty acid, GDF-15 growth differentiation factor-15