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Table 1 Characteristics of mothers in the pilot cohort

From: A pilot study of the association between maternal mid-pregnancy cholesterol and oxysterol concentrations and labor duration

Variable (N = 25)

Mean (SD)

Median (IQ)

n (%)

Range

Age (yrs)

30.7 (3.96)

  

21.6–37.8

Race

 White

  

23 (92)

 

 African American

  

1 (4.0)

 

 Asian

  

1 (4)

 

Education

 Level (yrs)

16.1 (2.1)

   

 College graduate

  

23 (92)

 

Pre-Pregnancy BMI (kg/m2)a

 Normal

  

10 (40)

 

 Overweight

  

7 (28)

 

 Obese

  

8 (32)

 

Nulliparous

  

16 (64)

 

Length of active labor (hrs)

 

7.0 (9.0)

 

0.67–30

Labor

 Labor induction

  

8 (32)

 

 Use of pain medicationb

  

19 (76)

 

Gestational agec

 

39 (1.0)

 

32–41

Birth weight (g)

3543 (333)

   

Mid-Pregnancy Serum Lipids (mg/dL)

 Total-C

250.6 (49.3)

  

131–374

 LDL-C

141.7 (41.1)

  

40–250

 HDL-C

78.9 (20.8)

  

33–117

 Triglycerides

172.8 (61.4)

  

87–398

Mid-Pregnancy Serum Oxysterols (ng/mL)d

 24-hydroxycholesterol (24OHC)

84.9 (29.3)

  

(42.8–146.9)

 25-hydroxycholesterol (25OHC)

18.4 (3.5)

  

(10.7–27.0)

 27-hydroxycholesterol (27OHC)

144.5 (39.3)

  

(66.9–211.7)

 7⍺-hydroxycholesterol (7⍺OHC)

47.4 (27.0)

  

(13.4–122.2)

 7β-hydroxycholesterol (7βOHC)

7.6 (5.0)

  

(0.06–21.3)

 7-ketocholesterol (7 KC)

5.0 (2.9)

  

(1.2–12.3)

 Total oxysterolsa

307.2 (72.0)

  

(145.9–473.9)

  1. aNormal BMI 18.5–24.9; overweight BMI 25–29.9; obese BMI 30–34.9
  2. bIncluding epidural analgesia (n = 16) and narcotic pain medications (n = 3)
  3. cGestational weeks at time of birth
  4. dRepresents the sum of 24OHC, 25OHC, 27OHC, 7⍺OHC, 7βOHC, and 7KC