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Table 2 Comparison of characteristics between children in different SUA deviation groups

From: Distribution of serum uric acid concentration and its association with lipid profiles: a single-center retrospective study in children aged 3 to 12 years with adenoid and tonsillar hypertrophy

Characteristics

SUA deviation groups

P value

Group 1

 < -1SD

(n = 742)

Group 2

-1 ≥ SD < 0

(n = 1902)

Group 3

0 ≥ SD < 1

(n = 1431)

Group 4

1 ≥ SD < 2

(n = 606)

Group 5

 ≥ 2SD

(n = 241)

Age, yr

6.0 ± 2.3bcde

6.3 ± 2.3acde

6.9 ± 2.6abde

7.6 ± 2.7abce

9.1 ± 2.9abcd

 < 0.001

Boys [n (%)]

453 (61.1)

1229 (64.6)

905 (63.2)

409 (67.5)

178 (73.9)

0.001

BMI z score

0.09 ± 1.27bcde

0.26 ± 1.19acde

0.46 ± 1.11abde

0.62 ± 1.05abc

0.82 ± 0.92abc

 < 0.001

SUA, mg/dL

2.92 ± 0.30bcde

3.78 ± 0.27acde

4.65 ± 0.26abde

5.54 ± 0.26abce

6.84 ± 0.70abcd

 < 0.001

FPG, mmol/L

4.40 ± 0.41ce

4.43 ± 0.47e

4.46 ± 0.51a

4.44 ± 0.46e

4.54 ± 0.49abd

 < 0.001

TC, mmol/L

3.83 ± 0.69

3.85 ± 0.69

3.85 ± 0.62

3.88 ± 0.67

3.78 ± 0.69

0.421

TG, mmol/L

0.80 ± 0.48cde

0.82 ± 0.41cde

0.88 ± 0.57abde

0.99 ± 0.59abce

1.16 ± 0.71abcd

 < 0.001

HDL-C, mmol/L

1.44 ± 0.31cde

1.42 ± 0.31cde

1.39 ± 0.28abe

1.37 ± 0.29abe

1.25 ± 0.26abcd

 < 0.001

Non-HDL-C, mmol/L

2.39 ± 0.62de

2.43 ± 0.63d

2.46 ± 0.58

2.51 ± 0.64ab

2.53 ± 0.64a

0.001

LDL-C, mmol/L

2.13 ± 0.59

2.16 ± 0.59

2.17 ± 0.54

2.19 ± 0.57

2.15 ± 0.56

0.313

ALT, U/L

12.06 ± 3.39bcde

12.67 ± 3.95acde

13.23 ± 4.38abde

14.09 ± 4.80abce

15.23 ± 5.26abcd

 < 0.001

AST, U/L

24.18 ± 5.26cde

24.11 ± 5.07cde

23.24 ± 4.78abde

22.57 ± 5.24abce

21.31 ± 4.92abcd

 < 0.001

GGT, U/L

9.30 ± 2.56bcde

10.02 ± 2.95acde

11.00 ± 3.75abde

12.20 ± 4.37abce

13.82 ± 5.50abcd

 < 0.001

ALP, U/L

227.75 ± 55.15bcde

235.49 ± 53.92acde

242.69 ± 58.55abde

258.21 ± 69.09abce

280.37 ± 88.92abcd

 < 0.001

Serum urea, μmol/L

4.46 ± 0.95cde

4.52 ± 0.98cde

4.63 ± 0.97ab

4.72 ± 0.95ab

4.76 ± 0.98ab

 < 0.001

Serum Cr, μmol/L

35.03 ± 7.07bcde

36.91 ± 7.24acde

39.08 ± 7.77abde

41.04 ± 8.11abce

45.89 ± 9.82abcd

 < 0.001

Dyslipidemia [n (%)]

96 (12.9)

305 (16.0)

241 (16.8)

141 (23.3)

73 (30.3)

 < 0.001

Hypercholesteremia [n (%)]

23 (3.1)

69 (3.6)

34 (2.4)

24 (4.0)

5 (2.1)

0.500

Hypertriglyceridemia [n (%)]

36 (4.9)

109 (5.7)

125 (8.7)

83 (13.7)

46 (19.1)

 < 0.001

Low HDL-C [n (%)]

51 (6.9)

163 (8.6)

134 (9.4)

66 (10.9)

45 (18.7)

 < 0.001

High Non-HDL-C [n (%)]

18 (2.4)

52 (2.7)

36 (2.5)

26 (4.3)

8 (3.3)

0.112

High LDL-C [n (%)]

5 (0.7)

11 (0.6)

5 (0.3)

5 (0.8)

0 (0.0)

0.467

  1. Compared with Group 1, a P < 0.05; compared with Group 2, b P < 0.05; compared with Group 3, c P < 0.05; compared with Group 4, d P < 0.05; compared with Group 5, e P < 0.05 (Bonferroni correction)