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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Excessive exogenous cholesterol activating intestinal LXRα-ABCA1/G5/G8 signaling pathway can not reverse atherosclerosis in ApoE−/− mice

Fig. 3

The influence of a high-fat diet on key targets of jejunum lipid metabolism in ApoE−/− mice. A The mRNA expression of targets related to lipid metabolism in the jejunum. B-D Representative western blots and relative quantitative analysis of NPC1L1, ABCG5, ABCG8, and ABCA1 in the proximal jejunum and liver. E Representative IHC staining images and quantitative analysis of LXRα and NPC1L1 in the jejunum. F-K Representative IF images and quantitative analysis of ABCG5 and ABCG8 in the proximal jejunum. In all experiments, n = 5, the P value indicates the comparison with the ApoE−/− + NF group. Values are expressed as mean ± SEM

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Lipids in Health and Disease

ISSN: 1476-511X