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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: Oxidized dietary lipids induce vascular inflammation and atherogenesis in post-menopausal rats: estradiol and selected antihyperlipidemic drugs restore vascular health in vivo

Fig. 7

Photomicrographs of the effects of estradiol and selected antihyperlipidemic drugs on the thoracic aorta of ovariectomized Wistar rats fed with thermoxidized palm oil diet. (7a) Sham (7b) OVX (7c) OVX + TPO (7d) EZE+ATV (7e) ATV (7f) ETD

Note hypertrophy of the peri-adventitial adipose tissue indicated by the black arrow in (OVX + TPO). Note the preservation of the elastic laminae of the tunica media, indicated by TM in all treatment groups. H&E staining of the rat aorta (x100 magnification)

OVX – ovariectomy; TPO – thermoxidized palm oil; EC – endothelial cells; TM – tunica media; TI – tunica intima; TA – tunica adventitia; PAT – peri-adventitial fat; ATV – atorvastatin; EZE – ezetimibe; ETD – estradiol

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Lipids in Health and Disease

ISSN: 1476-511X