Comparative serum lipid and immunohematological values among adult pulmonary tuberculosis and tuberculosis lymphadenitis cases and their association with sputum bacilli load and time to culture positivity in Northwestern Ethiopia

Table 1 Mean and median values with SD of age, BMI, immunohematological, serum lipid and creatinine values of PTB and TBLN patients in Northwestern Ethiopia, 2023

Dependent Variables	TBLN				PTB				P-Value
Dependent Variables	N	Mean	Median	SD	N	Mean	Median	SD	P-Value
Age (Year)	94	33.7	30.0	14.2	82	32.2	29.0	12.2	0.466
BMI (Kg/m2)	94	18.9	18.7	2.2	82	17.3	17.2	2.7	0.001
WBC*10⁹/L	83	7.4	7.4	2.1	61	7.2	6.9	2.6	0.534
Hb (g/L)	83	126.6	130.0	19.7	61	120.6	126.0	27.7	0.152
PLT*10⁹/L	83	301.04	292.0	101.8	60	315.9	308.0	131.0	0.463
CD4 cell*10⁶/L	40	759.0	792.5	294.3	48	456.	400.5	279.0	0.001
CHO (mmol/L)	94	2.5	2.7	1.4	82	2.4	2.4	0.9	0.749
TAG (mmol/L)	94	0.7	0.7	0.5	82	0.85	0.8	0.4	0.065
HDL-C (mmol/L)	94	0.8	0.9	0.4	82	0.6	0.6	0.3	0.019
Cr (µmol/L)	94	73.3	66.7	124.4	82	71.6	72.9	19.8	0.902
Time to grow (days)	57	11.6	11.1	6.0	64	14.0	8.7	13.0	0.194

BMI: body mass index, TB: Tuberculosis, WBC: White blood cell count, Hb: Hemoglobin, PLT: Platelet, N: number of cases, TBLN: tuberculous lymphadenitis, PTB: Pulmonary tuberculosis, CHO: Cholesterol, TAG: triacylglycerol, HDL: High density lipoprotein, UW: Underweight, SD: Standard deviation
Normal values for: BMI (Kg/m2): 18.5–24.9[47, 50]. WBC*10⁹/L: 4.8–10.8[51]. Hb (g/L): non-pregnant women (15 years of age and above): >120 g/L, Men (15 years of age and above):>130 g/L[49]. PLT*10⁹/L: 150–400. CD4 + Cells*10⁶/L: 396–1598 [52]. CHO (mmol/L) : <5.17 is normal, 5.17–6.18 is high, ≥ 6.21 is high.TAG (mmol/L): normal: <1.7, mildly increased: 1.7–5.6, moderately increased: 5.6 to 10.0, Very high: >10.0. .HDL-C (mmol/L): ≥1.55 excellent, < 1.03 is considered lower than desirable [53]. Cr (µmol/L): 61.9 to 114.9 µmol/L for men and 53 to 97.2 µmol/L for women [54, 55].

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