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Table 1 The relatively abundant proteins in each HDL subclass (vs. the other two subclasses) in human and rats samples

From: Proteomic and functional analysis of HDL subclasses in humans and rats: a proof-of-concept study

Species

L-HDL

M-HDL

S-HDL

Total

Human

C1QC, GLIPR2, LGALS3BP,THBS1, TLN1, TTR, FGA, FGB, FGG, CD5L, ATRN, FBLN1, A2M, FN1, CFH, C1R, APOB, CPN2, AMBP, IGHM, ITIH1, IGHA1, JCHAIN, ORM1, ORM2, APOE, C4BPA, KLKB1, ITIH2, APOL1, APOL1, CAMP, CPN1, CRTAC1, PZP, SERPING1, IGHG3, HBB, HLA-A

A1BG, AHSG, ANPEP, C2, C4B, CAT, CNDP1, F10, IGFALS, ITIH4, LUM, PGLYRP2, SAA4, SERPINA10, VWF, APOL1, CPN1, CPN2, CRTAC1, CP, APOD, C7, APOA4, GPLD1, C3, C1S, HGFAC, IGHG1, IGKC, ITIH2, ITIH1, FBLN1, CFH, C5, APOE,C4A, A2M, APCS, IGHA1, AMBP

BTD, C8G, CFHR2, F12, HRG, SERPINA6, VCL, A1BG, AHSG, C2, CAT, CNDP1, F10, IGFALS, ITIH4, LUM, PGLYRP2, SAA4, SERPINA10, VWF, GC, KNG1, APOH, C1RL, ACTG1, CFHR1, VTN, SERPINA3, HPX, CLEC3B, C8B, SERPINF2, PLG, APOA1, C7, APOA2, C3, C1S, GSN, TF, IGHG1, AFM, IGKC, CP, CFB

85

Rat

APOC4, APOB, THBS1, TGFBI, PSAP, FBLN1, APON, APOC1, CPN1, C4BPA, C1R, FN1, ITIH2, MUG1, APOE, CFH, ITIH1, KLKB1, APOA1, CPN2

THBS1, TGFBI, PSAP, FBLN1, APON, APOC1, PKM, CSF1R, CPN1, C1R, VWF, GPX3, C8B, LUM, F10, EGFR, APCS, C1S, ITIH4, IGH-1A, HGFAC, SERPING1, IGFALS, C3, C5, MUG1, ITIH2, CFH, CP, ITIH3, ITIH1

VCL, SERPINA6, SELL, PGLYRP2, CFHR1, C9, C2, SOD3,F12, CFD, CA2, ALDOB, SERPIND1, PROC, GPX3, F9, C8B, SERPINA3M, LUM, IL1RAP, F10, EGFR, APCS, HPX, CFB, CFI, ITIH4, AFM, C1S, GC, F2, IGG-2A, C8G,C8A, CP, IGFALS, VTN, HRG, IGH-1A, AHSG, HGFAC

68

  1. As described in Figs. 4a and 5a, 85 proteins and 68 proteins were identified to be significantly changed in concentration in the HDL subclasses from human and rat samples, respectively. The relatively abundant proteins in each HDL subclass were defined as the proteins at higher concentration in that subclass than in the other two HDL subclasses. For example, the relatively abundant proteins of L-HDL identified in rat samples were the proteins that has higher concentration in the L-HDL subclass than in the M-HDL or S-HDL subclasses