Lipids in Health and Disease

Table 2 The 5-year and 3-year AUCs of the proposed model and baseline model in the training and validation sets

From: Widely targeted quantitative lipidomics and prognostic model reveal plasma lipid predictors for nasopharyngeal carcinoma

Clinical outcome	Training set		Validation set
Clinical outcome	AUC (95% CI) of the proposed model ^a	AUC (95% CI) of the baseline model ^b	AUC (95% CI) of the proposed model ^a	AUC (95% CI) of the baseline model ^b
DMFS
5-year	0.797 (0.719–0.874)	0.739 (0.636–0.841)	0.800 (0.696–0.904)	0.691 (0.559–0.823)
3-year	0.787 (0.706–0.868)	0.734 (0.625–0.844)	0.786 (0.678–0.895)	0.698 (0.560–0.835)
PFS
5-year	0.795 (0.700–0.891)	0.707 (0.594–0.82)	0.802 (0.687–0.917)	0.698 (0.557–0.838)
3-year	0.766 (0.66–0.873)	0.708 (0.592–0.824)	0.791 (0.669–0.912)	0.698 (0.549–0.846)
OS
5-year	0.768 (0.598–0.939)	0.699 (0.615–0.783)	0.739 (0.551–0.926)	0.65 (0.446–0.854)
3-year^c	-	-	-	-

DMFS Distant metastasis-free survival, PFS Progression-free survival, OS Overall survival, AUC Area under the receiver operating characteristic curve, CI Confidence interval
^aThe proposed model was developed based on lipid and clinical biomarkers
^bThe baseline model was developed based on only clinical biomarkers
^cAUCs of the survival models in predicting 3-year OS were not available by reason of only 1 patient dead within 3 years in the training set

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