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Table 1 Clinical characteristics of study subjects by hs-CRP and lipids levels

From: Interactive effect of increased high sensitive C-reactive protein and dyslipidemia on cardiovascular diseases: a 12-year prospective cohort study

Variables

All subjects

N = 4128

Normal lipids and normal hs-CRP

n = 1586 (38.42%)

Dyslipidemia and normal hs-CRP

n = 716 (17.34%)

Normal lipids and increased hs-CRP

n = 1053 (25.51%)

Dyslipidemia and increased hs-CRP

n = 773 (18.73%)

H/χ2

P

Age (years)

58.95 (52.24, 67.00)

57.26 (51.00, 63.99)

56.81 (50.08, 64.88)

61.85 (55.24, 71.04)

61.01 (54.10, 70.37)

181.22

< 0.001*

Gender n (%)

       

Women

2444 (59.21)

894 (55.37)

404 (56.42)

652 (61.92)

494 (63.91)

17.86

< 0.001*

Men

1684 (40.79)

692 (43.63)

312 (43.58)

401 (38.08)

279 (36.09)

  

Smoking n (%)

       

Yes

1005 (24.35)

428 (26.99)

177 (24.72)

238 (22.60)

162 (21.96)

12.62

0.006*

No

3123 (75.65)

1158 (73.01)

539 (75.28)

815 (77.40)

611 (79.04)

  

Drinking n (%)

       

Yes

891 (21.58)

371 (23.39)

161 (22.49)

213 (20.22)

146 (18.89)

  

No

3237 (78.42)

1215 (76.61)

555 (77.51)

840 (79.77)

627 (81.11)

7.87

0.049*

Hypertension n (%)

       

Yes

2015 (48.81)

642 (40.48)

366 (51.12)

555 (52.71)

452 (58.47)

80.87

< 0.001*

No

2113 (51.19)

944 (59.52)

350 (48.88)

498 (47.29)

321 (41.53)

  

DM n (%)

       

Yes

468 (11.34)

109 (6.87)

107 (14.94)

113 (10.73)

139 (17.98)

75.05

< 0.001*

No

3660 (88.66)

1477 (93.13)

609 (85.06)

940 (89.27)

634 (82.02)

  

Overweight/Obese n (%)

      

Yes

2072 (50.19)

608 (38.34)

375 (52.37)

568 (53.94)

521 (67.40)

188.03

< 0.001*

No

2056 (49.81)

978 (61.66)

241 (47.63

485 (46.06)

252 (32.60)

  

SBP (mmHg)

134 (123, 14)

131 (120, 140)

134 (123, 143)

135 (125, 141.5)

137 (127, 145)

56.75

< 0.001*

DBP (mmHg)

82 (78, 89)

81 (78, 88)

83 (79, 90)

82 (78, 89)

83 (79, 89)

27.79

< 0.001*

BMI (kg/m2)

24.01 (21.93, 26.42)

23.00 (21.14, 25.30)

24.23 (22.38, 26.40)

24.44 (22.04, 26.71)

25.65 (23.19, 27.91)

280.60

< 0.001*

HDL-C (mg/dL)

51.35 (43.63, 59.85)

54.05 (47.10, 61.40)

43.24 (37.07, 56.37)

53.67 (47.30, 61.39)

44.10 (37.45, 57.53)

483.24

< 0.001*

LDL-C(mg/dL)

102.32 (84.94, 120.08)

99.61 (85.33, 115, 06)

103.47 (79.54, 128.96)

104.25 (88.80, 119.30)

105.02 (83.01, 131.85)

28.31

< 0.001*

Non-HDL-C (mg/dL)

133.59 (111.68, 157.14)

124.32 (104, 63, 144.40)

147.49 (119, 79, 179, 44)

130.12 (110, 42, 148.65)

154.05 (124.52, 183.78)

445.63

< 0.001*

TC (mg/dL)

185.33 (162.93, 210.42)

179.92 (161.62, 201.16)

193.44 (161.97, 236.97)

183.78 (167.06, 204.63)

200.00 (167.57, 240.93)

168.56

< 0.001*

TG (mg/dL)

116.81 (79.65, 176.99)

91.15 (67.26, 124.78)

202.66 (117.92, 278.32)

100.89 (73.45, 137.61)

217.70 (144.25, 285.84)

1335.55

< 0.001*

ApoAI (g/L)

1.57 (1.38, 1.80)

1.62 (1.44, 1.84)

1.49 (1.30, 1.73)

1.61 (1.43, 1.82)

1.49 (1.31, 1.72)

140.34

< 0.001*

ApoB (g/L)

0.90 (0.75, 1.08)

0.86 (0.73, 1.02)

0.97 (0.77, 1.16)

0.88 (0.75, 1.04)

1.00 (0.80, 1.18)

155.79

< 0.001*

Lp(a) (mg/L)

87.80 (43.75, 174.68)

86.78 (44.40, 159.03)

79.88 (36.53, 183.25)

94.00 (48.75, 185.65)

89.10 (42.95, 185.00)

13.14

0.004*

TC/HDL-C

3.64 (3.07, 4.22)

3.29 (2.84, 3.76)

4.22 (3.67, 4.89)

3.42 (2.93, 3.92)

4.33 (3.70, 5.00)

1082.97

< 0.001*

TG/HDL-C

2.27 (1.44, 3.74)

1.68 (1.18, 2.39)

4.17 (2.65, 6.39)

1.89 (1.29, 2.65)

4.62 (3.22, 6.59)

1559.64

< 0.001*

LDL-C/HDL-C

2.02 (1.64, 2.39)

1.84 (1.52, 2.17)

2.28 (1.87, 2.73)

1.95 (1.56, 2.29)

2.29 (1.92, 2.79)

506.78

< 0.001*

  1. Notes: *: significance at 0.05. Normal hs-CRP: hs-CRP < 1 mg/L, increased hs-CRP: hs-CRP ≥ 1 mg/L. DBP: diastolic blood pressure, SBP: systolic blood pressure, TG: triglycerides; TC: total cholesterol, HDL-C: high-density lipoprotein cholesterol, LDL-C: low-density lipoprotein cholesterol, BMI: body mass index, ApoAI: apolipoprotein AI, ApoB: apolipoprotein B, Lp(a): lipoprotein(a). Values are presented as M: median (IQR: interquartile range) or n (%). For each quantitative variable, the P-value is obtained by the Kruskal Wallis H test; for each categorical variable, the P-value is obtained through Pearson’s χ2-test