Table 1 Baseline characteristics of patients by tertiles of lipoprotein (a)
From: Lipoprotein (a) and myocardial infarction: impact on long-term mortality
Variables | Lp(a)(mg/L) | P Value | |||
|---|---|---|---|---|---|
Tertile 1 | Tertile 2 | Tertile 3 | Total | ||
(n = 145)(49–201) | (n = 146)(202–338) | (n = 145)(342–1200) | (n = 436)(49–1200) | ||
Hospitalization time (days) | 11 (8–14) | 10 (7–14) | 11 (8–15) | 11 (8–14) | 0.343 |
Age (years) | 62 (52–72) | 64 (54–74) | 68 (60–76) | 65 (54–74) | < 0.001 |
Male | 108 (74.5%) | 113 (77.4%) | 102 (70.3%) | 323 (74.1%) | 0.386 |
BMI (kg/m2) | 24.36 ± 3.36 | 24.21 ± 3.60 | 24.12 ± 3.46 | 24.23 ± 3.47 | 0.838 |
Heart rate (beat/min) | 72 (65–82) | 76 (68–86) | 78 (70–89) | 76 (68–86) | 0.005 |
Pulse pressure (mmHg) | 52 (45–60) | 49 (40–58) | 50 (40–60) | 50 (41–59) | 0.078 |
Current smoker | 53 (36.6%) | 54 (37.0%) | 40 (27.6%) | 147 (33.7%) | 0.161 |
Current drinker | 35 (24.1%) | 46 (31.5%) | 26 (17.9%) | 107 (24.5%) | 0.027 |
Hypertension | 73 (50.3%) | 75 (51.4%) | 81 (55.9%) | 229 (52.5%) | 0.606 |
Diabetes mellitus | 28 (19.3%) | 16 (11.0%) | 28 (19.3%) | 72 (16.5%) | 0.086 |
Previous stroke | 12 (8.3%) | 17 (11.6%) | 22 (15.2%) | 51 (11.7%) | 0.188 |
Previous PCI | 5 (3.4%) | 7 (4.8%) | 8 (5.5%) | 20 (4.6%) | 0.694 |
Previous MI | 2 (1.4%) | 4 (2.7%) | 7 (4.8%) | 13 (3.0%) | 0.215 |
LVEF (%) | 59 (55–62) | 58 (54–60) | 54 (49–57) | 57 (53–59) | < 0.001 |
NLR | 3.99 (2.46–6.46) | 4.42 (2.76–7.54) | 4.19 (2.82–7.47) | 4.20 (2.69–7.09) | 0.218 |
Monocyte (*109/L) | 0.49 (0.36–0.68) | 0.46 (0.36–0.67) | 0.48 (0.36–0.60) | 0.48 (0.36–0.64) | 0.813 |
Hemoglobin (g/L) | 137 ± 21 | 134 ± 20 | 130 ± 20 | 134 ± 21 | 0.022 |
Platelet (*109/L) | 205 (162–236) | 198 (157–244) | 192 (159–240) | 200 (161–239) | 0.868 |
TG (mmol/L) | 1.37 (1.05–1.99) | 1.43 (1.06–1.94) | 1.32 (0.98–1.65) | 1.37 (1.02–1.86) | 0.086 |
TC (mmol/L) | 3.98 (3.41–4.72) | 4.29 (3.68–4.97) | 4.03 (3.38–4.74) | 4.08 (3.46–4.88) | 0.202 |
LDL-C (mmol/L) | 2.42 (1.96–3.00) | 2.65 (2.18–3.11) | 2.50 (1.99–3.07) | 2.53 (2.01–3.09) | 0.210 |
HDL-C (mmol/L) | 1.01 (0.84–1.19) | 1.03 (0.86–1.15) | 1.03 (0.89–1.18) | 1.02 (0.86–1.18) | 0.953 |
VLDL-C (mmol/L) | 0.51 (0.38–0.70) | 0.53 (0.40–0.69) | 0.48 (0.36–0.61) | 0.51 (0.37–0.66) | 0.088 |
ApoA-I (g/L) | 1.07 (0.94–1.22) | 1.09 (0.91–1.20) | 1.06 (0.94–1.22) | 1.07 (0.92–1.21) | 0.889 |
ApoB (g/L) | 0.79 (0.69–0.91) | 0.82 (0.70–0.98) | 0.76 (0.68–0.98) | 0.79 (0.69–0.96) | 0.367 |
Lp(a) (mg/L) | 149 (120–178) | 264 (235–293) | 480 (412–612) | 264 (178–412) | < 0.001 |
eGFR (ml/(min*1.73m2)) | 100 (90–113) | 97 (86–109) | 89 (73–104) | 96 (82–109) | < 0.001 |
Uric acid (umol/L) | 340 (280–393) | 366 (313–423) | 403 (320–459) | 366 (305–432) | < 0.001 |
FBG (mmol/L) | 5.83 (5.23–6.93) | 6.05 (5.31–7.14) | 6.50 (5.45–7.89) | 6.08 (5.31–7.34) | 0.007 |
NSTEMI | 72 (49.7%) | 77 (52.7%) | 71 (49.0%) | 220 (50.5%) | 0.790 |
STEMI | 73 (50.3%) | 69 (47.3%) | 74 (51.0%) | 216 (49.5%) | |
Number of occluded arteries | 102 (70.3%) | 100 (68.5%) | 93 (64.1%) | 295 (67.7%) | 0.510 |
PCI/CABG | 112 (77.2%) | 104 (71.2%) | 96 (66.2%) | 312 (71.6%) | 0.114 |
Antiplatelet agent | 139 (95.9%) | 127 (87.0%) | 132 (91.0%) | 398 (91.3%) | 0.133 |
ACEI/ARB | 73 (50.3%) | 62 (42.5%) | 56 (38.6%) | 191 (43.8%) | 0.302 |
Beta-blocker | 75 (51.7%) | 88 (60.3%) | 83 (57.2%) | 246 (56.4%) | 0.046 |
CCB | 16 (11.0%) | 19 (13.0%) | 19 (13.1%) | 54 (12.4%) | 0.675 |
Diuretic | 17 (11.7%) | 18 (12.3%) | 37 (25.5%) | 72 (16.5%) | 0.001 |
Statins | 137 (94.5%) | 129 (88.4%) | 127 (87.6%) | 393 (90.1%) | 0.374 |