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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Combining albumin deficiency and acute exercise reduces hepatic lipid droplet size in mice

Fig. 6

Large lipid droplets (LDs) in WT mice were maintained using carbon backbone potentially from glycogen during exercise A. Liver gene expression related to lipogenesis. DGAT1: Diacylglycerol O-acyltransferase 1; DGAT2: Diacylglycerol O-acyltransferase 2; FAS: Fatty acid synthase; PLIN2: Perilipin 2. B Liver gene expression related to G-3-P pathway. GPD-1: glycerol-3-phosphate dehydrogenase 1; GPAT1: Glycerol-3-phosphate acyltransferase 1; GPAT4: Glycerol-3-phosphate acyltransferase 4. C Hepatic G-3-P concentration. D Plasma glycerol concentration. E Plasma triacylglycerol (TAG) concentration. F GPD-1 protein expression. EX: exercise, CON: control. Analysis by ANOVA. n = 6 per group. Data are presented as the mean ± S.E.M. mRNA results normalized to 18S and protein results normalized to β-actin. Main effect of genotype, †P < 0.01, ‡P < 0.05. EX different from CON within a genotype, * P < 0.05

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