Association of serum uric acid with hepatic steatosis detected by controlled attenuation parameter in the United States population

Table 4 Association between SUA (mg/dL) and NAFLD among US adults aged ≥ 20 years

	Crude	P values	Model 1	P values	Model 2	P values	Model 1^a	P values	Model 2^a	P values
CAP ≥ 248 (dB/m)
SUA	1.40 (1.33, 1.48)	< 0.01	1.35 (1.28, 1.43)	< 0.01	1.29 (1.13, 1.47)	< 0.01	1.38 (1.31, 1.45)	< 0.01	1.35 (1.27, 1.42)	< 0.01
Male	1.29 (1.20, 1.38)	< 0.01	1.28 (1.18, 1.38)	< 0.01	1.16 (0.96, 1.39)	0.14	1.30 (1.21, 1.39)	< 0.01	1.28 (1.19, 1.38)	< 0.01
Female	1.55 (1.43, 1.68)	< 0.01	1.45 (1.33, 1.58)	< 0.01	1.55 (1.24, 1.93)	< 0.01	1.48 (1.37, 1.61)	< 0.01	1.43 (1.32, 1.56)	< 0.01
CAP ≥ 268 (dB/m)
SUA	1.35 (1.28, 1.42)	< 0.01	1.31 (1.24, 1.38)	< 0.01	1.30 (1.14, 1.47)	< 0.01	1.33 (1.26, 1.40)	< 0.01	1.30 (1.23, 1.37)	< 0.01
Male	1.23 (1.15, 1.32)	< 0.01	1.23 (1.14, 1.32)	< 0.01	1.10 (0.92, 1.30)	0.18	1.24 (1.16, 1.32)	< 0.01	1.22 (1.14, 1.31)	< 0.01
Female	1.50 (1.39, 1.62)	< 0.01	1.42 (1.31, 1.54)	< 0.01	1.71 (1.36, 2.15)	< 0.01	1.45 (1.34, 1.57)	< 0.01	1.40 (1.29, 1.51)	< 0.01
CAP ≥ 280 (dB/m)
SUA	1.33 (1.27, 1.40)	< 0.01	1.30 (1.24, 1.38)	< 0.01	1.27 (1.12, 1.43)	< 0.01	1.31 (1.25, 1.38)	< 0.01	1.28 (1.22, 1.35)	< 0.01
Male	1.24 (1.16, 1.32)	< 0.01	1.24 (1.15, 1.33)	< 0.01	1.08 (0.91, 1.28)	0.19	1.24 (1.16, 1.33)	< 0.01	1.23 (1.15, 1.32)	< 0.01
Female	1.45 (1.35, 1.56)	< 0.01	1.39 (1.28, 1.51)	< 0.01	1.66 (1.32, 2.09)	< 0.01	1.40 (1.30, 1.51)	< 0.01	1.35 (1.25, 1.46)	< 0.01

^a Missing values of covariates were imputed with multiple imputations
Model 1: age, race and BMI were adjusted
Model 2: age, race, BMI, waist circumference, education levels, ratio of family income, ALT, AST, GGT, serum creatinine, triglyceride, serum cholesterol, HDL-C, LDL-C, glycohemoglobin, HOMA-IR, dietary fat intake, smoking habits, MET, hypertension and diabetes were adjusted

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