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Table 3 HDL subpopulations and glycation according to the studied groups

From: Adipose tissue dysfunction serum markers are associated with high density lipoprotein size and glycation in the early stages of type 2 diabetes

 

Normoglycemic

n = 17

Prediabetes

n = 17

T2D

n = 18

P value

HDL subpopulations

    

HDL2b (%)

8.5 ± 3.6

7.7 ± 2.7

6.2 ± 2.6

0.074

HDL2a (%)

17.2 ± 3.7

15.2 ± 4.3

13.4 ± 5.1 *

0.047

HDL3a (%)

23.2 ± 2.3

24.0 ± 2.4 *

21.2 ± 4.4 †

0.033

HDL3b (%)

25.4 ± 2.6

27.0 ± 2.5

26.4 ± 2.7

0.224

HDL3c (%)

25.8 ± 6.9

26.9 ± 5.8

32.8 ± 11 *

0.028

HDL mean diameter (nm)

8.49 ± 0.20

8.44 ± 0.17

8.32 ± 0.20 *

0.033

HDL glycation

    

HDL- fructosamine

4.55 ± 0.79

4.67 ± 0.85

5.18 ± 1.1

0.139

HDL- carbonyls

96.4 ± 22

98.5 ± 29

102.3 ± 24

0.824

HDL-AGE

7.5 (6.8–9.9)

12.4 (8.2–16.3)

14.3 (8.8–19) *†

0.009

  1. Values are expressed as the mean ± standard deviation, median (interquartile range)
  2. * P < 0.05 vs. normoglycemic, † p < 0.05 vs. prediabetes. The P value for means was calculated by ANOVA with Bonferroni correction, and that for medians was calculated by the Kruskal‒Wallis test. HDL: high density lipoproteins; AGE: advanced glycation products
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Lipids in Health and Disease

ISSN: 1476-511X