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Table 2 Hazard ratios and 95% confidence intervals for CVD risk stratified by cumulative CVAI indicators

From: Association of the time course of Chinese visceral adiposity index accumulation with cardiovascular events in patients with hypertension

Index

Case, n (%)

Incidence ratea

Model 1

Model 2

Model 3

CumCVAI

  

Quartile 1

204(5.32)

8.23(7.17–9.44)

Reference

Reference

Reference

Quartile 2

278(7.24)

11.55(10.27–12.99)

1.29(1.08–1.55)

1.30(1.09–1.56)

1.21(1.01–1.45)

Quartile 3

337(8.78)

14.40(12.94–16.03)

1.49(1.25–1.78)

1.51(1.27–1.80)

1.29(1.07–1.54)

Quartile 4

365(9.51)

16.03(14.46–17.76)

1.52(1.28–1.82)

1.54(1.29–1.84)

1.35(1.13–1.61)

P for trend

  

< 0.01

< 0.01

< 0.01

TWA-CVAI

Quartile 1

213(5.55)

8.73(7.63–9.98)

Reference

Reference

Reference

Quartile 2

259(6.75)

10.82(9.58–12.22)

1.17(0.97–1.40)

1.17(0.98–1.41)

1.09(0.91–1.31)

Quartile 3

346(9.02)

14.73(13.25–16.36)

1.50(1.26–1.78)

1.52(1.28–1.80)

1.28(1.07–1.52)

Quartile 4

366(9.54)

15.79(14.25–17.49)

1.51(1.27–1.79)

1.52(1.28–1.81)

1.35(1.14–1.61)

P for trend

  

< 0.01

< 0.01

< 0.01

Cumulative burden

  

= 0

491(6.21)

9.86(9.02–10.77)

Reference

Reference

Reference

> 0

693(9.32)

15.32(14.22–16.51)

1.40(1.24–1.57)

1.41(1.25–1.58)

1.26(1.12–1.43)

Time exposure duration

     

0 year

166(5.07)

7.95(6.83–9.25)

Reference

Reference

Reference

2 years

204(7.00)

11.23(9.79–12.88)

1.26(1.03–1.55)

1.27(1.03–1.56)

1.21(0.99–1.49)

4 years

189(7.41)

11.99(10.40-13.82)

1.28(1.04–1.58)

1.29(1.05–1.59)

1.18(0.95–1.45)

6 years

230(8.93)

14.63(12.86–16.65)

1.54(1.26–1.88)

1.55(1.27–1.90)

1.39(1.13–1.70)

Index

Case, n (%)

Incidence rate a

Model 1

Model 2

Model 3

8 years

228(9.71)

16.08(14.12–18.31)

1.66(1.35–2.03)

1.67(1.36–2.05)

1.42(1.15–1.74)

10 years

167(9.92)

16.20(13.92–18.85)

1.71(1.37–2.12)

1.73(1.39–2.15)

1.43(1.14–1.78)

P for trend

  

< 0.01

< 0.01

< 0.01

Combination of CumCVAI and CVAI slope

  

CumCVAI<median, Slope<0

186(6.74)

10.75(9.31–12.41)

Reference

Reference

Reference

CumCVAI<median, Slope ≥ 0

296(6.02)

9.38(8.37–10.51)

0.98(0.81–1.18)

0.98(0.82–1.18)

1.01(0.84–1.21)

CumCVAI ≥ median, Slope<0

240(9.35)

14.96(13.65–16.38)

1.24(1.03–1.51)

1.25(1.03–1.52)

1.12(0.92–1.36)

CumCVAI ≥ median, Slope ≥ 0

462(9.04)

15.70(13.83–17.82)

1.32(1.11–1.56)

1.33(1.12–1.58)

1.22(1.03–1.46)

P for trend

  

< 0.01

< 0.01

< 0.01

  1. Model 1: adjusted for age and sex;
  2. Model 2: adjusted for age, sex, smoking status, drinking status, education, and physical activity;
  3. Model 3: further adjusted for SBP, eGFR, hs-CRP, FBG, LDL-c, Antidiabetic agents, Antihypertensive agents, Lipid-lowering agents;
  4. Incidence ratea: per 1000 person-years
  5. Cut off value of CVAI = 110.6; Median of cumulative CVAI was 332983.38
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Lipids in Health and Disease

ISSN: 1476-511X