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Table 4 Association between the Fatty Liver Index (FLI) and blood coagulation parameters in study participantsa stratified by glucose tolerance status

From: Association between fatty liver index and blood coagulation markers: a population-based study

 

Model 1b

Model 2c

𝛃 estimate

95%

confidence interval

P value

𝛃 estimate

95%

confidence interval

P value

Normal glucose tolerance

Antithrombin III [mg/dL]

-0.042

-0.080; -0.004

0.032

-0.061

-0.103; -0.019

0.004

Ln D-dimers

0.003

0.001; 0.005

0.003

0.004

0.002; 0.006

< 0.001

Faktor VIII [%]

0.206

0.068; 0.343

0.003

0.239

0.087; 0.392

0.002

Fibrinogen D [mg/dL]

0.544

0.303; 0.785

< 0.001

0.502

0.235; 0.769

< 0.001

aPTT [s]d

0.001

-0.013; 0.012

0.940

-0.009

-0.023; 0.005

0.203

Protein C [%]

0.163

0.098; 0.229

< 0.001

0.116

0.045; 0.187

0.002

Protein S [%]

0.305

0.177; 0.433

< 0.001

0.215

0.074; 0.355

0.003

Quick value [%]

0.082

0.047; 0.117

< 0.001

0.076

0.037; 0.115

< 0.001

INRe

-0.049

-0.070; − 0.028

< 0.001

-0.045

-0.069; -0.022

< 0.001

Prediabetes

Antithrombin III [mg/dL]

-0.072

-0.113; -0.031

< 0.001

-0.097

-0.139; -0.054

< 0.001

Ln D-dimers

0.001

-0.001; 0.003

0.251

0.001

-0.001; 0.003

0.528

Faktor VIII [%]

0.279

0.132; 0.427

< 0.001

0.251

0.097; 0.405

0.002

Fibrinogen D [mg/dL]

0.210

-0.055; 0.474

< 0.001

0.169

-0.112; 0.450

0.237

aPTT [s]d

-0.017

-0.031; -0.003

0.021

-0.018

-0.033; -0.002

0.023

Protein C [%]

0.078

0.007; 0.149

0.032

0.055

-0.018; 0.129

0.141

Protein S [%]

0.149

0.011; 0.287

0.035

0.127

-0.017; 0.272

0.083

Quick value [%]

0.030

-0.005; 0.065

0.096

0.032

-0.005; 0.070

0.088

INRe

-0.018

-0.039; 0.003

0.089

-0.020

-0.042; 0.002

0.077

Diabetes, newly diagnosed and known

Antithrombin III [mg/dL]

-0.175

-0.318; -0.032

0.017

-0.120

-0.275; 0.034

0.125

Ln D-dimers

0.003

-0.003; 0.008

0.306

0.003

-0.003; 0.009

0.319

Faktor VIII [%]

0.152

-0.179; 0.483

0.364

0.114

-0.250; 0.479

0.533

Fibrinogen D [mg/dL]

0.160

-0.437; 0.758

0.594

0.320

-0.330; 0.971

0.329

aPTT [s]d

0.002

-0.035; 0.040

0.903

-0,002

-0.043; -0.039

0.919

Protein C [%]

-0.019

-0.241;0.203

0.865

0.007

-0.228; 0.242

0.952

Protein S [%]

0.119

-0.267; 0.506

0.540

0.035

-0.385; 0.454

0.869

Quick value [%]

-0.047

-0.186; 0.092

0.499

-0.023

-0.170; 0.125

0.758

INRe

0.010

-0.100; − 0.121

0.851

-0.016

-0.134; 0.101

0.786

  1. a After exclusion of individuals with anticoagulation therapy (n = 29); b dependent variables: blood coagulation markers, exposure variable: Fatty Liver Index, adjusted for age, alcohol consumption, sex, education, smoking and physical activity; c dependent variables: blood coagulation markers, exposure variable: Fatty Liver Index, additionally adjusted for stroke, hypertension, myocardial infarction, non HDL cholesterol d activated partial thromboplastin time; e international normalized ratio, INR times 100