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Fig. 3 | Lipids in Health and Disease

Fig. 3

From: Heme oxygenase 1 alleviates nonalcoholic steatohepatitis by suppressing hepatic ferroptosis

Fig. 3

HO-1 deficiency exacerbates hepatic ferroptosis in mice with NASH. (A, B, C, D) The levels of MDA, 4-HNE, GSH, and SOD in the liver. (E, F) The levels of total iron and ferrous iron contents in the liver. (G) Western blot analysis of SLC7A11, GPX4, Ferritin, ACSL4, LOX in liver tissue. Values are the mean ± SD (n = 6 per group). *P < 0.05, **P < 0.01 compared to the WT ND group; #P < 0.05, ##P < 0.01 compared to the WT HFD group

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