Table 1 Characteristics of patients in the CKD and non-CKD groups.^*

Age, years

44.0 (39.25, 50.00)

44.0 (39.00, 49.00)

0.269

male/female, %

57.1/42.9

53.0/47.0

0.279

History of hypertension^**, n (%)

57 (25.2)

58 (7.3)

< 0.001

eGFR, mL/min/1.73 m²

36.96 (25.75,49.58)

94.33 (81.57,104.74)

< 0.001

HCV genotype 1/2, %

62.8/37.2

63.2/36.8

0.921

HCV load, log IU/mL

5.0 (5.0,6.0)

5.0 (5.0,6.0)

0.109

Metabolic profile

BMI, kg/m²

25.45 (22.95,27.60)

24.52 (21.59,27.16)

< 0.001

HOMA-IR

2.40 (1.95,3.48)

2.21 (1.77,2.55)

< 0.001

TC, mmol/L

5.76 (4.83,6.39)

5.38 (4.66,6.01)

0.001

TG, mmol/L

2.36 (2.08,2.57)

1.94 (1.69,2.20)

< 0.001

LDL-C, mmol/L

2.99 (2.63,3.25)

2.86 (2.72,3.02)

< 0.001

HDL-C, mmol/L

1.18 (1.00,1.42)

1.22 (1.05,1.44)

0.234

ALT, IU/L

68.68 (39.56,102.04)

68.15 (40.64,96.10)

0.395

AST, IU/L

77.67 (46.91,107.61)

81.99 (49.44,110.20)

0.416

ALP, IU/L

113.00 (70.92,151.16)

113.47 (72.08,152.41)

0.691

GGT, IU/L

43.41 (34.71,59.55)

43.93 (33.64,57.70)

0.781

Serum CRP, mg/L

1.89 (1.40,2.34)

1.73 (1.23,2.22)

0.002

Liver steatosis, n (%)

121 (53.5)

300 (37.7)

< 0.001

CAP, dB/m

233 (211,264)

215 (189,258)

< 0.001

Steatosis grade (%)

S1

56.2

52.66

0.427

S2

9.92

14.67

S3

33.88

32.67

Elastic modulus, kPa

11.8 (9.1,13.5)

11.0 (8.9,13.1)

0.125

Liver fibrosis^***, %

10.2/51.8/38.0

9.7/58.6/31.7

0.158