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Table 2 Genotype and allele frequencies of PNPLA3 rs738409 and TM6SF2 rs58542926 variants in the CKD and non-CKD groups

From: Metabolic disorders induced by PNPLA3 and TM6SF2 gene variants affect chronic kidney disease in patients infected with non-genotype 3 hepatitis C virus

Variant

CKD, n (%)

non-CKD, n (%)

χ 2

P value

PNPLA3 rs738409

Genotype

   

CC

80 (35.4)

393 (49.4)

17.13

< 0.001

CG

117 (51.8)

347 (43.6)

  

GG

29 (12.8)

56 (7.0)

  

Allele

    

C

277 (61.3)

1133 (71.2)

15.62

< 0.001

G

175 (38.7)

459 (28.8)

  

TM6SF2 rs58542926

Genotype

   

CC

209 (92.5)

658 (82.7)

-

< 0.001

CT

15 (6.6)

136 (17.1)

  

TT

2 (0.9)

2 (0.2)

  

Allele

    

C

433 (95.8)

1452 (91.2)

10.34

0.001

T

19 (4.2)

140 (8.8)

  
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Lipids in Health and Disease

ISSN: 1476-511X