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Table 1 Baseline characteristics of patients categorized by apoB tertiles

From: Apolipoprotein B is associated with CT-angiographic progression beyond low-density lipoprotein cholesterol and non-high-density lipoprotein cholesterol in patients with coronary artery disease

Variables

Low

Medium

High

P value

N

180

182

182

 

Age, years

67.3 ± 9.9

63.6 ± 10.6

62.3 ± 10.9

< 0.001

Male, n (%)

101 (56.1)

104 (57.1)

102 (56.0)

0.972

BMI, kg/m2

24.0 ± 2.9

24.9 ± 3.0

25.0 ± 2.7

0.002

Hypertension, n (%)

131 (72.8)

135 (74.2)

129 (70.9)

0.778

Diabetes, n (%)

81 (45.0)

86 (47.3)

100 (54.9)

0.139

Obstructive CAD, n (%)

92 (51.1)

87 (47.8)

93 (51.1)

0.768

Smoking status, n (%)

55 (30.6)

51 (28.0)

65 (35.7)

0.273

SBP, mmHg

143.1 ± 17.2

140.3 ± 15.7

143.0 ± 18.1

0.203

DBP, mmHg

77.1 ± 9.3

78.2 ± 10.1

79.5 ± 10.6

0.076

WBC count, ×10E9/L

6.98 ± 1.82

6.78 ± 1.31

7.08 ± 1.76

0.206

Creatinine, µmol/L

78.44 ± 19.65

77.23 ± 21.34

79.60 ± 21.02

0.552

eGFR, mL/min/1.73m2

80.18 ± 17.15

83.88 ± 17.45

82.34 ± 18.01

0.132

Uric acid, mmol/L

355.06 ± 113.60

375.48 ± 102.82

403.22 ± 108.34

< 0.001

FPG, mmol/L

6.09 ± 2.22

6.48 ± 4.41

7.10 ± 3.39

0.020

HbA1c, (%)

6.56 ± 1.56

6.74 ± 1.67

7.01 ± 1.91

0.045

TC, mmol/L

4.21 ± 1.00

4.92 ± 1.02

5.63 ± 1.03

< 0.001

TG, mmol/L

1.15 (0.85, 1.51)

1.56 (1.06, 2.29)

1.96 (1.43, 2.88)

< 0.001

HDL-C, mmol/L

1.18 ± 0.30

1.14 ± 0.30

1.07 ± 0.26

0.001

LDL-C, mmol/L

2.51 ± 0.71

3.12 ± 0.91

3.60 ± 0.93

< 0.001

Lipoprotein(a), mg/L

130.20 (72.53, 248.80)

128.60 (73.00, 222.50)

120.65 (61.00, 293.00)

0.909

Non-HDL-C, mmol/L

3.03 ± 0.93

3.78 ± 0.93

4.56 ± 0.95

< 0.001

Anti-platelet medication, n (%)

162 (90.0)

153 (84.1)

158 (86.9)

0.245

Statins, n (%)

155 (86.1)

156 (85.7)

155 (85.2)

0.967

β-blocker, n (%)

80 (44.4)

68 (37.4)

70 (38.5)

0.335

ACEI/ARB, n (%)

113 (62.8)

106 (58.2)

98 (53.8)

0.227

Glucose-lowering therapy, n (%)

67 (37.2)

72 (39.6)

81 (44.5)

0.353

Initial GS

6.0 (3.5, 13.0)

7.0 (3.5, 12.3)

7.0 (4.0, 15.0)

0.626

  1. Data are mean ± SD, or median with interquartile range, or frequencies with percentage, as appropriate
  2. ApoB apolipoprotein B, BMI body mass index, CAD coronary artery disease, SBP systolic blood pressure, DBP diastolic blood pressure, WBC white cell counts, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, HbA1c hemoglobinA1c, TC total cholesterol, TG triglycerides, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, ACEI angiotensin converting enzyme inhibitor, ARB angiotensin receptor blocker, GS Gensini Score
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Lipids in Health and Disease

ISSN: 1476-511X