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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: The East Asian-specific LPL p.Ala288Thr (c.862G > A) missense variant exerts a mild effect on protein function

Fig. 2

Functional analysis of the LPL p.Ala288Thr missense variant. (A) Western blot (WB) analysis of LPL expression in transfected HEK-293T cells without heparin. (B) WB analysis of postheparin LPL expression in cell medium from HEK-293T cells. (C) WB analysis of postheparin LPL expression in cell lysates from HEK-293T cells. (D) WB analysis of LPL expression in transfected COS-7 cells without heparin. (E) WB analysis of postheparin LPL expression in cell medium from COS-7 cells. (F) WB analysis of postheparin LPL expression in cell lysates from COS-7 cells. LPL, lipoprotein lipase; WT, wild-type; p.A288T, LPL p.Ala288Thr; ns, not significant; * P < 0.05

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Lipids in Health and Disease

ISSN: 1476-511X