Table 1 Demographic baselines and clinical features of the five HTG-AP patients studied

Age (years; at the current disease onset)

41

29

57

42

59

Sex

Male

Male

Male

Male

Male

Body mass index (kg/m²)

28.07

27.17

25.06

28.72

26.81

Putative triggering factor(s)

HFD & Alcohol (~ 30 g)^a

HFD

HFD & Alcohol (~ 40 g) ^a

Alcohol (~ 80 g) ^a

Alcohol (~ 80 g) ^a

TG at AP onset (mmol/L)

30.1

22.7

13.1

18.8

96.7

APACHE II score

9

7

17

30

21

Severity of AP

 RAC

Severe

Moderate severe

Severe

Severe

Severe

 DBC

Severe

Severe

Critical

Critical

Critical

Complications

 Acute respiratory distress

 syndrome

No

No

Yes

Yes

Yes

 Acute kidney injury

Yes

No

Yes

Yes

Yes

 Abdominal compartment

 syndrome

No

No

No

Yes

No

 Infected pancreatic necrosis

No

Yes

Yes

Yes

Yes

 Abdominal hemorrhage

No

No

No

No

Yes

Length of hospital stay (days)

7

18

115

48

42

Length of ICU stay (days)

6

5

58

48

42

Outcomes

Survival

Survival

Survival

Death

Death

Medical histories

 AP

No

Yes

Yes

Yes

No

 Number of previous AP episodes

0

1

2

1

0

 Age of the first AP episode (years)

41

27

52

40

59

 Diabetes mellitus (prior

 treatment)

Yes, 3 years

(Metformin, 1000 mg/day)

No

No

No

No

 HTG

Yes, 15 years

Yes, 3 years

Yes, 5 years

Yes, 10 years

Yes, 20 years

 Hypertension

Yes, 5 years

No

Yes, 8 years

No

Yes, 10 years

 Fatty liver

Yes, 10 years

Yes^b

Yes^b

No

Yes^b

 Smoking

No

No

Yes, 30 years

(30 cigarettes/day)

Yes, 15 years

(40 cigarettes/day)

Yes, 30 years

(30 cigarettes/day)

 Alcohol consumption (duration,

 average weekly intake

 quantity of ethanol)

Yes, 15 years

(~ 200 g/week)

Yes, 5 years

(~ 80 g/week)

Yes, 30 years

(~ 240 g/week)

Yes, 20 years

(~ 400 g/week)

Yes, 30 years

(~ 160 g/week)