Table 1 Population characteristics across frailty status
Characteristics | Total (N = 17,052) | Non-Frailty (N = 13,233) | Frailty (N = 3819) | P-value |
|---|---|---|---|---|
Age, years | 59 (11.90) | 57 (11.46) | 63 (12.38) | 2.05E-30 |
Gender | Â | Â | Â | 1.16E-18 |
 Female | 6059 (52.43%) | 3973 (49.31%) | 2086 (61.84%) |  |
 Male | 5779 (47.57%) | 4282 (50.69%) | 1497 (38.16%) |  |
Ethnicity | Â | Â | Â | 2.63E-13 |
 White | 5545 (73.78%) | 3869 (75.30%) | 1676 (69.17%) |  |
 Black | 2389 (9.60%) | 1520 (8.18%) | 869 (13.90%) |  |
 Other | 3904 (16.62%) | 2866 (16.52%) | 1038 (16.93%) |  |
Education level | Â | Â | Â | 2.66E-22 |
 Below High School | 3397 (17.66%) | 2043 (14.39%) | 1354 (27.54%) |  |
 High School and above | 8441 (82.34%) | 6212 (85.61%) | 2229 (72.46%) |  |
Marital status | Â | Â | Â | 2.49E-18 |
 Non-Married | 5056 (37.01%) | 3143 (33.09%) | 1913 (48.86%) |  |
 Married | 6782 (62.99%) | 5112 (66.91%) | 1670 (51.14%) |  |
Family income | Â | Â | Â | 8.30E-50 |
 Poor | 2012 (10.47%) | 1108 (7.55%) | 904 (19.27%) |  |
 Near poor | 3375 (19.96%) | 2048 (16.06%) | 1327 (31.75%) |  |
 Non-poor | 6451 (69.57%) | 5099 (76.39%) | 1352 (48.98%) |  |
Smoking status | Â | Â | Â | 2.33E-15 |
 Never | 5980 (50.35%) | 4392 (53.18%) | 1588 (41.78%) |  |
 Former | 3703 (31.48%) | 2495 (30.78%) | 1208 (33.61%) |  |
 Current | 2155 (18.17%) | 1368 (16.04%) | 787 (24.61%) |  |
BMI, kg/m2 | 29 (6.64) | 29 (6.05) | 31 (7.86) | 1.81E-21 |
SBP, mmHg | 126 (18.40) | 125 (17.69) | 129 (20.06) | 1.41E-15 |
DBP, mmHg | 70 (11.69) | 71 (11.18) | 68 (12.88) | 7.33E-16 |
HEI-2015 | Â | Â | Â | 1.07E-12 |
 Quartile 1 | 2960 (26.04%) | 1929 (24.80%) | 1031 (29.78%) |  |
 Quartile 2 | 2959 (24.67%) | 1961 (23.65%) | 998 (27.75%) |  |
 Quartile 3 | 2959 (24.49%) | 2108 (24.36%) | 851 (24.89%) |  |
 Quartile 4 | 2960 (24.80%) | 2257 (27.20%) | 703 (17.58%) |  |
eGFR, ml/min per 1.73 m2 | Â | Â | Â | 4.68E-46 |
 ≥ 90 | 5104 (43.56%) | 3895 (45.87%) | 1209 (36.60%) |  |
 60 to 89 | 5106 (45.58%) | 3633 (47.14%) | 1473 (40.90%) |  |
 < 60 | 1628 (10.85%) | 727 (7.00%) | 901 (22.50%) |  |
Type 2 DM | 2188 (13.96%) | 883 (8.15%) | 1305 (31.49%) | 8.66E-49 |
CVD | 2100 (14.75%) | 692 (7.81%) | 1408 (35.69%) | 1.57E-52 |
Statins use | 3296 (26.63%) | 1830 (21.86%) | 1466 (41.01%) | 4.36E-26 |
Anti-diabetic drug use | 2012 (13.20%) | 837 (8.11%) | 1175 (28.56%) | 1.62E-43 |
Anti-hypertensive drug use | 1122 (8.49%) | 680 (7.45%) | 442 (11.62%) | 2.61E-08 |
TG, mg/dl | 109 (76, 158) | 105 (74, 153) | 121 (86, 175) | 1.54E-15 |
TC, mg/dl | 197.94 (41.36) | 200.41 (39.95) | 190.49 (44.51) | 8.45E-16 |
HDL-C, mg/dl | 55.64 (17.05) | 56.41 (16.85) | 53.33 (17.43) | 2.84E-10 |
LDL-C, mg/dl | ||||
 Martin-Hopkins | 118.97 (35.72) | 121.10 (34.57) | 112.54 (38.28) | 9.28E-16 |
 Friedewald | 117.17 (36.32) | 119.70 (35.11) | 109.53 (38.77) | 3.83E-19 |
 Sampson | 119.71 (36.29) | 122.14 (35.17) | 112.38 (38.57) | 5.84E-18 |
RC, mg/dl | ||||
 Martin-Hopkins | 23.33 (8.92) | 22.90 (8.69) | 24.62 (9.47) | 2.45E-10 |
 Friedewald | 25.13 (13.51) | 24.30 (13.08) | 27.63 (14.45) | 1.54E-15 |
 Sampson | 22.59 (11.79) | 21.86 (11.45) | 24.78 (12.49) | 3.90E-17 |
RC to TC Ratio, % | ||||
 Martin-Hopkins | 11.15 (8.86, 14.31) | 10.71 (8.61, 13.74) | 12.47 (9.92, 15.51) | 1.91E-28 |
 Friedewald | 11.21 (7.93, 16.17) | 10.63 (7.62, 15.36) | 13.27 (9.44, 18.39) | 4.44E-28 |
 Sampson | 10.30 (7.39, 14.56) | 9.74 (7.04, 13.83) | 12.13 (8.75, 16.38) | 2.45E-29 |
RC to LDL-C Ratio, % | ||||
 Martin-Hopkins | 18.78 (14.95, 24.31) | 17.95 (14.40, 23.27) | 21.32 (16.93, 27.39) | 1.49E-33 |
 Friedewald | 18.81 (13.15, 28.14) | 17.65 (12.50, 26.35) | 22.74 (16.06, 33.69) | 3.35E-33 |
 Sampson | 17.15 (12.16, 24.86) | 15.99 (11.51, 23.47) | 20.70 (14.80, 29.47) | 5.77E-34 |