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Table 6 Summary of meta-analysis results

From: Lipid profiles in patients with juvenile idiopathic arthritis: a systematic literature review and meta-analysis

Factors

Design

N

Heterogeneity test

Effect model

Outcomes

I2(%)

P

SMD(95%CI)

Z

P

BMI

CS

4

86.4

0.001

random

-0.736 (-1.987, 0.514)

1.15

0.248

 

CC

2

0.0

0.659

random

-0.040 (-0.278, 0.199)

0.33

0.745

 

CO

5

76.8

0.002

random

0.177 (-0.273, 0.627)

0.77

0.441

HDL

CS

4

88.8

< 0.001

random

-1.526 (-3.995, 0.944)

1.21

0.226

 

CO

2

64.7

0.092

random

-0.652 (-1.379, 0.075)

1.76

0.079

LDL

CS

4

88.1

< 0.001

random

0.737 (-1.047, 2.520)

0.81

0.418

 

CO

1

-

-

-

0.128 (-0.427, 0.683)

0.45

0.651

VLDL

CS

4

63.3

0.043

random

-0.411 (-0.774, -0.048)

2.22

0.026

TG

CS

5

80.5

0.001

random

-0.171 (-0.709, 0.368)

0.62

0.534

 

CC

1

-

-

-

0.573 (0.119, 1.026)

2.48

0.013

 

CO

5

91.0

< 0.001

random

0.687 (-0.164, 1.538)

1.58

0.114

TC

CS

4

62.1

0.048

random

0.060 (-0.407, 0.528)

0.25

0.800

 

CC

1

-

-

-

0.522 (0.070, 0.973)

2.26

0.024

 

CO

4

79.2

0.002

random

-0.362 (-0.949, 0.226)

1.21

0.228

HDL-C

CS

2

37.8

0.205

random

0.165 (-0.368, 0.697)

0.61

0.544

 

CC

1

-

-

-

-0.154 (-0.598, 0.291)

0.68

0.499

 

CO

4

64.7

0.037

random

-0.949 (-1.432, -0.466)

3.85

< 0.001

LDL-C

CS

2

0.0

0.476

fixed

0.236 (-0.182, 0.653)

1.11

0.269

 

CC

1

-

-

-

0.651 (0.195, 1.107)

2.80

0.005

 

CO

4

24.9

0.262

fixed

0.043 (-0.217, 0.303)

0.32

0.745

Apo-A1

CS

1

-

-

-

-1.438 (-2.165, -0.711)

3.87

0.001

 

CO

2

69.3

0.071

fixed

-0.878 (-1.361, -0.395)

3.56

< 0.001

Apo-B

CS

2

46.9

0.170

fixed

0.180 (-0.243, 0.604)

0.83

0.404

 

CO

1

-

-

-

0.341 (-0.334, 1.016)

0.99

0.322

  1. Apo apolipoprotein, BMI Body mass index, CC A case‒control study, CO Cohort study, CS A cross-sectional study, HDL High-density lipoprotein, HDL-C High-density lipoprotein cholesterol, LDL Low-density lipoprotein, LDL-C Low-density lipoprotein cholesterol, TC Total cholesterol, TG Triglyceride, VLDL Very low-density lipoprotein