Factors | Design | N | Heterogeneity test | Effect model | Outcomes | |||
---|---|---|---|---|---|---|---|---|
I2(%) | P | SMD(95%CI) | Z | P | ||||
BMI | CS | 4 | 86.4 | 0.001 | random | -0.736 (-1.987, 0.514) | 1.15 | 0.248 |
 | CC | 2 | 0.0 | 0.659 | random | -0.040 (-0.278, 0.199) | 0.33 | 0.745 |
 | CO | 5 | 76.8 | 0.002 | random | 0.177 (-0.273, 0.627) | 0.77 | 0.441 |
HDL | CS | 4 | 88.8 | < 0.001 | random | -1.526 (-3.995, 0.944) | 1.21 | 0.226 |
 | CO | 2 | 64.7 | 0.092 | random | -0.652 (-1.379, 0.075) | 1.76 | 0.079 |
LDL | CS | 4 | 88.1 | < 0.001 | random | 0.737 (-1.047, 2.520) | 0.81 | 0.418 |
 | CO | 1 | - | - | - | 0.128 (-0.427, 0.683) | 0.45 | 0.651 |
VLDL | CS | 4 | 63.3 | 0.043 | random | -0.411 (-0.774, -0.048) | 2.22 | 0.026 |
TG | CS | 5 | 80.5 | 0.001 | random | -0.171 (-0.709, 0.368) | 0.62 | 0.534 |
 | CC | 1 | - | - | - | 0.573 (0.119, 1.026) | 2.48 | 0.013 |
 | CO | 5 | 91.0 | < 0.001 | random | 0.687 (-0.164, 1.538) | 1.58 | 0.114 |
TC | CS | 4 | 62.1 | 0.048 | random | 0.060 (-0.407, 0.528) | 0.25 | 0.800 |
 | CC | 1 | - | - | - | 0.522 (0.070, 0.973) | 2.26 | 0.024 |
 | CO | 4 | 79.2 | 0.002 | random | -0.362 (-0.949, 0.226) | 1.21 | 0.228 |
HDL-C | CS | 2 | 37.8 | 0.205 | random | 0.165 (-0.368, 0.697) | 0.61 | 0.544 |
 | CC | 1 | - | - | - | -0.154 (-0.598, 0.291) | 0.68 | 0.499 |
 | CO | 4 | 64.7 | 0.037 | random | -0.949 (-1.432, -0.466) | 3.85 | < 0.001 |
LDL-C | CS | 2 | 0.0 | 0.476 | fixed | 0.236 (-0.182, 0.653) | 1.11 | 0.269 |
 | CC | 1 | - | - | - | 0.651 (0.195, 1.107) | 2.80 | 0.005 |
 | CO | 4 | 24.9 | 0.262 | fixed | 0.043 (-0.217, 0.303) | 0.32 | 0.745 |
Apo-A1 | CS | 1 | - | - | - | -1.438 (-2.165, -0.711) | 3.87 | 0.001 |
 | CO | 2 | 69.3 | 0.071 | fixed | -0.878 (-1.361, -0.395) | 3.56 | < 0.001 |
Apo-B | CS | 2 | 46.9 | 0.170 | fixed | 0.180 (-0.243, 0.604) | 0.83 | 0.404 |
 | CO | 1 | - | - | - | 0.341 (-0.334, 1.016) | 0.99 | 0.322 |