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Table 3 Clinical characteristics and biomarkers of patients in the ALD-without-PLC group and ALD-associated-PLC group

From: Increased age, bilirubin, international normalized ratio, and creatinine score to triglyceride ratio are associated with alcohol-associated primary liver carcinoma: a single-centered retrospective study

variables

ALD-without-PLC

ALD-associated-PLC

P

drinking time (years)

28.91 ± 10.22

34.57 ± 9.7

< 0.01

average daily drinking (g/d)

127.85 ± 80.35

175.47 ± 93.07

< 0.01

ALT (U/L)

47.14 ± 79.31

30.98 ± 30.99

0.15

AST (U/L)

63.96 ± 99.14

44.58 ± 29.47

0.01

GGT (U/L)

234.98 ± 322.19

136.26 ± 326.18

0.05

AKP (U/L)

128.67 ± 96.71

139.45 ± 107.05

0.48

TBIL (umol/L)

56.93 ± 84.79

47.68 ± 83.98

0.48

DBIL (umol/L)

34 ± 60.96

27.08 ± 58.14

0.46

PT-INR

1.4 ± 1.48

1.37 ± 0.24

0.88

AST to ALT ratio

1.74 ± 0.98

1.9 ± 0.71

0.41

Cho (mmol/L)

4.1 ± 1.61

3.46 ± 1.38

< 0.01

TG (mmol/L)

1.61 ± 1.99

0.82 ± 0.29

< 0.01

HDL-C (mmol/L)

1.03 ± 0.46

1.02 ± 0.42

0.92

LDL-C (mmol/L)

2.27 ± 1.22

1.9 ± 1.42

0.06

DF

7.86 ± 24.49

13.49 ± 13.64

0.03

MELD

7.81 ± 6.83

9.2 ± 4.63

0.08

ABIC

6.96 ± 1.71

7.74 ± 0.88

< 0.01

GAHS

6.54 ± 1.01

6.75 ± 0.7

0.07

ABIC score/TG (L/mmol)

6.59 ± 4.25

10.44 ± 3.27

< 0.01

  1. ALD: alcohol-associated liver disease; PLC: primary liver carcinoma; TG: triglyceride; Cho: cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; ALT: alanine aminotransferase; AST: aspartate transaminase; GGT: gamma-glutamyl transferase; AKP: alkaline phosphatase; TBIL: total bilirubin; DBIL: direct bilirubin; PT-INR: international normalized ratio of prothrombin time; DF: Maddrey discriminant function; MELD: Model for End-stage Liver Disease; ABIC: age-bilirubin-international normalized ratio (INR)-creatinine; GAHS: Glasgow alcoholic hepatitis scores