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Fig. 7 | Lipids in Health and Disease

Fig. 7

From: Sirt6 enhances macrophage lipophagy and improves lipid metabolism disorder by regulating the Wnt1/β-catenin pathway in atherosclerosis

Fig. 7

Mechanisms of action of Sirt6 for promoting lipophagy. A–F Sirt6, SNF2H, Wnt1, LC3-II/GAPDH, and P62 were examined by immunoblotting and quantitative analysis (n = 6). G–M The LC3-II/GAPDH ratio, P62, Wnt1, β-catenin, PLIN2, and adipophilin expression were analyzed quantitatively by immunoblotting (n = 6). N The 10% input of Co-IP. O–P Immunoblots and quantitative analyses of the 10% input. Q-R Co-immunoprecipitation (Co-IP) experiments for Sirt6 and SNF2H. One way ANOVA showed that there was statistical significance among groups (P < 0.05)

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Lipids in Health and Disease

ISSN: 1476-511X