Table 2 GRADE evidence profile
Outcomes | Certainty assessment | Effect | Certainty | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
① | ② | ③ | ④ | ⑤ | ⑥ | No. of Studies | No. of Individuals | Rate (95%CI) | ||
TC | Not serious | Very serious | Not serious | Not serious | Not serious | Large effect | 9RCTs | 629 | MD: -21.76 (-33.73 to -9.79) | ⨁⨁⨁◯ Moderate |
TGs | Not serious | Very serious | Not serious | Not serious | Not serious | Large effect | 9RCTs | 629 | MD:-26.51 (-41.23 to -11.78) | ⨁⨁⨁◯ Moderate |
LDL-C | Not serious | Very serious | Not serious | Not serious | Not serious | Large effect | 9RCTs | 629 | MD:-16.13 (-25.91 to -6.34) | ⨁⨁⨁◯ Moderate |
HDL-C | Not serious | Serious | Not serious | Not serious | Not serious | Large effect | 9RCTs | 629 | MD:3.26 (1.28 to 5.25) | ⨁⨁⨁⨁ High |
FBG | Not serious | Very serious | Not serious | Not serious | Not serious | None | 9RCTs | 599 | MD:-4.41 (-12.42 to 3.60) | ⨁⨁◯◯ Low |
AST | Not serious | Very serious | Not serious | Not serious | Not serious | None | 9RCTs | 583 | MD:-4.41 (-12.42 to 3.60) | ⨁⨁◯◯ Low |
ALT | Not serious | Very serious | Not serious | Not serious | Not serious | Large effect | 9RCTs | 584 | MD:-5.50 (-9.77 to -1.23) | ⨁⨁⨁◯ Moderate |