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Table 1 Baseline clinical characteristics of patients

From: Lipoprotein(a) is a new prognostic factor in patients with psoriasis and coronary artery disease: a retrospective cohort study

Parameter

Entire cohort (n = 295)

Low Lp(a) group (n = 148)

High Lp(a) group (n = 147)

P

Age, years (n = 295)

58.69 ± 9.82

58.39 ± 10.47

58.99 ± 9.14

0.604

Male, % (n = 295)

260(88.1)

133(89.9)

127(86.4)

0.357

BMI, kg/m2 (n = 295)

26.09 ± 3.33

26.47 ± 3.28

25.70 ± 3.35

0.097

Current smoker, % (n = 295)

195(66.1)

97(65.5)

98(66.7)

0.838

Hypertension, % (n = 295)

165(55.9)

87(58.8)

78(53.1)

0.322

Diabetes, % (n = 295)

122(41.4)

62(41.9)

60(40.8)

0.851

Hyperlipidemia, % (n = 295)

278(94.2)

140(94.6)

138(93.9)

0.792

Family history of CAD, % (n = 295)

41(13.9)

21(14.2)

20(13.6)

0.885

Previous stroke, % (n = 295)

27(9.2)

16(10.8)

11(7.5)

0.322

Peripheral vascular disease, % (n = 295)

15(5.1)

10(6.8)

5(3.4)

0.190

CKD, % (n = 295)

26(8.8)

10(6.8)

16(10.9)

0.211

ACS, % (n = 295)

186(63.1)

93(62.8)

93(63.3)

0.939

Psoriasis characteristics

 Psoriatic arthritis, % (n = 256)

10(3.9)

7(5.3)

3(2.4)

0.372

 Disease duration, years (n = 267)

20(15, 30)

20(15, 30)

22.5(15, 30)

0.814

 PASI score (n = 245)

6.2(2.2, 13.25)

5.5(1.1, 12.55)

7.9(3.8, 13.5)

0.500

 Topical treatment, % (n = 256)

167(65.2)

88(67.2)

79(63.2)

0.504

 Phototherapy, % (n = 256)

33(12.9)

18(13.7)

15(12.0)

0.678

 Nonbiologic systemic treatment, % (n = 256)

105(41.0)

53(40.5)

52(41.6)

0.853

 Biologic treatment, % (n = 256)

27(10.5)

12(9.2)

15(12)

0.460

Medication at discharge (n = 293)

 Aspirin, %

271(92.5)

138(93.2)

133(91.7)

0.622

 P2Y12 inhibitors, %

238(81.2)

119(80.4)

119(82.1)

0.715

 ACEIs/ARBs, %

148(50.5)

75(50.7)

73(50.3)

0.955

 β-blockers, %

247(84.3)

117(79.1)

130(89.7)

0.013

 Statin, %

284(96.9)

143(96.6)

141(97.2)

1.000

 Calcium channel blockers, %

58(19.8)

33(22.3)

25(17.2)

0.278

  1. Abbreviations: ACS Acute coronary syndrome, ACEIs Angiotensin-converting enzyme inhibitors, ARBs Angiotensin receptor blockers, BMI Body mass index, CAD Coronary artery disease, CKD Chronic kidney disease, Lp(a) Lipoprotein(a), PASI Psoriasis area severity index