Skip to main content

Table 2 Biochemical results, coronary characteristics and clinical outcomes of patients

From: Lipoprotein(a) is a new prognostic factor in patients with psoriasis and coronary artery disease: a retrospective cohort study

Parameter

Entire cohort (n = 295)

Low Lp(a) group (n = 148)

High Lp(a) group

(n = 147)

P

Laboratory values

 Platelet count, × 109/L (n = 295)

224(184, 262)

216(180, 257)

233(187, 275)

0.038

 hsCRP, mg/L (n = 272)

1.57(0.65, 3.72)

1.34(0.62, 2.99)

1.85(0.70, 5.76)

0.012

 eGFR, ml/min/1.73m2 (n = 295)

87.50 ± 20.03

89.09 ± 19.87

85.91 ± 20.13

0.174

 TC, mmol/L (n = 295)

3.82(3.22, 4.46)

3.71(3.13, 4.40)

3.88(3.42, 4.56)

0.029

 LDL-c, mmol/L (n = 295)

2.26(1.76, 2.86)

2.18(1.61, 2.94)

2.29(1.86, 2.82)

0.174

 HDL-c, mmol/L (n = 295)

1.06(0.90, 1.26)

1.04(0.88, 1.22)

1.11(0.92, 1.29)

0.168

 Triglycerides, mmol/L (n = 295)

1.49(1.08, 2.00)

1.53(1.10, 2.20)

1.40(1.06, 1.83)

0.037

Coronary characteristics

 Presence of plaque, % (n = 293)

289(98.6)

144(98)

145(99.3)

0.619

Culprit vessel (n = 293)

 LAD, %

253(86.3)

130(88.4)

123(84.2)

0.296

 LCX, %

199(67.9)

100(68.0)

99(67.8)

0.968

 RCA, %

213(72.7)

99(67.3)

114(78.1)

0.039

 LM, %

45(15.4)

27(18.4)

18(12.3)

0.152

No. of diseased vessels (n = 293)

 1, %

65(22.2)

33(22.4)

32(21.9)

0.913

 2, %

72(24.6)

37(25.2)

35(24.0)

0.812

 3, %

152(51.9)

74(50.3)

78(53.4)

0.597

Target lesion morphology

 Bifurcation lesion, % (n = 175)

22(12.6)

8(9.5)

14(15.4)

0.243

 Chronic total occlusion, % (n = 175)

46(26.3)

20(23.8)

26(28.6)

0.475

 Complex lesion (lesion of type B2 or C), % (n = 175)

140(80)

63(75)

77(84.6)

0.112

 PCI, % (n = 295)

172(58.3)

82(55.4)

90(61.2)

0.311

Framingham risk score for estimation of 10-years of cardiovascular diseases risk

 Low-risk, % (n = 295)

46(15.6)

23(15.5)

23(15.6)

0.980

 Moderate-risk, % (n = 295)

28(9.5)

13(8.8)

15(10.2)

0.677

 High-risk, % (n = 295)

221(74.9)

112(75.7)

109(74.1)

0.762

 CABG, % (n = 295)

22(7.5)

12(8.1)

10(6.8)

0.670

 Follow-up time, months (n = 280)

36(20, 52)

35(21.75, 50.25)

37(18.75, 53)

0.847

 All-cause death, % (n = 280)

10(3.6)

3(2.1)

7(5.1)

0.311

 Rehospitalization, % (n = 280)

12(4.3)

3(2.1)

9(6.5)

0.069

  1. Abbreviations: CABG Coronary artery bypass grafting, eGFR Estimated glomerular filtration rate, HDL-c High-density lipoprotein cholesterol, hsCRP High-sensitivity C-reactive protein, LAD Left anterior descending artery, LCX Left circumflex artery, LDL-c Low-density lipoprotein cholesterol, LM Left main artery, Lp(a) Lipoprotein(a), PCI Percutaneous coronary intervention, RCA Right circumflex artery, TC Total cholesterol