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Table 2 Performance assessment of the noninvasive indices and models for the prediction of MAFLD in the NHANES cohort

From: Comparison of the diagnostic performance of twelve noninvasive scores of metabolic dysfunction-associated fatty liver disease

Variables

AUC (95% CI)

SEN (95% CI)

SPE (95% CI)

PPV (95% CI)

NPV (95% CI)

Cutoff value

METS-IR

0.846 (0.837–0.854)

0.818 (0.805–0.830)

0.717 (0.703–0.732)

0.748 (0.735–0.761)

0.793 (0.779–0.807)

40.887

TyG

0.746 (0.735–0.757)

0.727 (0.713–0.741)

0.640 (0.625–0.656)

0.675 (0.661–0.689)

0.695 (0.680–0.711)

8.497

TyG-BMI

0.850 (0.841–0.859)

0.819 (0.807–0.831)

0.727 (0.712–0.741)

0.755 (0.741–0.768)

0.796 (0.782–0.810)

240.222

TyG-WC

0.863 (0.855–0.871)

0.859 (0.848–0.870)

0.702 (0.687–0.717)

0.748 (0.735–0.760)

0.829 (0.816–0.842)

822.332

TyG-WtHR

0.853 (0.845–0.862)

0.810 (0.798–0.823)

0.740 (0.726–0.754)

0.762 (0.749–0.775)

0.791 (0.778–0.805)

5.066

HSI

0.835 (0.826–0.844)

0.799 (0.787–0.812)

0.722 (0.708–0.737)

0.747 (0.734–0.761)

0.778 (0.764–0.792)

37.131

VAI

0.741 (0.730–0.752)

0.711 (0.697–0.726)

0.658 (0.643–0.673)

0.681 (0.667–0.696)

0.689 (0.674–0.705)

1.494

FLI

0.859 (0.851–0.867)

0.839 (0.828–0.851)

0.714 (0.700-0.729)

0.751 (0.738–0.764)

0.812 (0.799–0.826)

49.405

LAP

0.834 (0.825–0.843)

0.787 (0.773-0.800)

0.725 (0.711–0.740)

0.746 (0.733–0.760)

0.768 (0.754–0.782)

45.180

ZJU

0.845 (0.836–0.854)

0.826 (0.814–0.838)

0.711 (0.696–0.726)

0.746 (0.733–0.759)

0.799 (0.786–0.813)

38.522

FSI

0.858 (0.850–0.867)

0.768 (0.755–0.782)

0.775 (0.761–0.789)

0.778 (0.765–0.792)

0.765 (0.751–0.779)

-1.068

K-NAFLD

0.838 (0.829–0.847)

0.771 (0.757–0.784)

0.748 (0.734–0.762)

0.759 (0.745–0.772)

0.760 (0.746–0.774)

-1.023

  1. Abbreviations: AUC Area under the receiver operating characteristic curve, SPE Specificity, SEN Sensitivity, NPV Negative predictive value, PPV Positive predictive value