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Table 3 Performance assessment of the noninvasive indices and models for the prediction of MAFLD in the Western China cohort

From: Comparison of the diagnostic performance of twelve noninvasive scores of metabolic dysfunction-associated fatty liver disease

Variables

AUC (95% CI)

SEN (95% CI)

SPE (95% CI)

PPV (95% CI)

NPV (95% CI)

Cutoff value

METS-IR

0.896 (0.888–0.905)

0.876 (0.859–0.892)

0.760 (0.745–0.774)

0.630 (0.609–0.650)

0.929 (0.919–0.939)

35.223

TyG

0.776 (0.762–0.789)

0.685 (0.662–0.708)

0.736 (0.721–0.751)

0.547 (0.525–0.570)

0.834 (0.820–0.847)

8.680

TyG-BMI

0.903 (0.895–0.911)

0.836 (0.817–0.854)

0.811 (0.798–0.825)

0.674 (0.653–0.695)

0.914 (0.904–0.924)

211.515

TyG-WC

0.873 (0.864–0.883)

0.865 (0.848–0.882)

0.724 (0.709–0.739)

0.594 (0.574–0.614)

0.920 (0.909–0.930)

714.871

TyG-WtHR

0.866 (0.856–0.876)

0.904 (0.889–0.919)

0.667 (0.651–0.683)

0.559 (0.539–0.578)

0.937 (0.927–0.947)

4.198

HSI

0.873 (0.863–0.883)

0.842 (0.824–0.860)

0.736 (0.721–0.751)

0.598 (0.578–0.619)

0.909 (0.898–0.920)

33.032

VAI

0.773 (0.759–0.786)

0.755 (0.733–0.776)

0.657 (0.641–0.673)

0.506 (0.486–0.527)

0.852 (0.838–0.865)

1.426

FLI

0.879 (0.869–0.888)

0.848 (0.830–0.866)

0.751 (0.736–0.765)

0.613 (0.593–0.634)

0.914 (0.903–0.924)

25.876

LAP

0.854 (0.843–0.864)

0.810 (0.790–0.829)

0.740 (0.725–0.755)

0.592 (0.571–0.613)

0.893 (0.882–0.905)

28.720

ZJU

0.900 (0.891–0.908)

0.865 (0.848–0.882)

0.773 (0.759–0.787)

0.640 (0.620–0.661)

0.925 (0.915–0.935)

34.549

FSI

0.872 (0.863–0.882)

0.904 (0.889–0.919)

0.676 (0.660–0.692)

0.565 (0.546–0.585)

0.938 (0.928–0.948)

-2.408

K-NAFLD

0.836 (0.825–0.847)

0.810 (0.790–0.829)

0.715 (0.700-0.731)

0.570 (0.550–0.591)

0.890 (0.878–0.902)

-2.589

  1. Abbreviations: AUC Area under the receiver operating characteristic curve, SPE specificity, SEN Sensitivity, NPV Negative predictive value, PPV Positive predictive value