Table 1 Baseline characteristics
Variables | Overall cohort | After matching | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
Non-switcher (n = 1187) | Switcher (n = 401) | SMD | Non-switcher (n = 749) | Switcher (n = 393) | SMD | |||||
No. of patients | % | No. of patients | % | No. of patients | % | No. of patients | % | |||
Age groups, Mean (SD) | 74.3 | 3.95 | 74.5 | 4.0 | -0.061 | 74.3 | 3.8 | 74.6 | 4.0 | -0.057 |
65–69 | 31 | 2.6 | 12 | 3.0 | -0.023 | 14 | 1.9 | 8 | 2.0 | -0.012 |
70–74 | 724 | 61.0 | 234 | 58.4 | 0.054 | 461 | 61.6 | 234 | 59.5 | 0.041 |
75–80 | 299 | 25.2 | 95 | 23.7 | 0.035 | 182 | 24.3 | 93 | 23.7 | 0.015 |
80–84 | 108 | 9.1 | 53 | 13.2 | -0.131 | 82 | 11.0 | 51 | 13.0 | -0.062 |
≥ 85 | 25 | 2.1 | 7 | 1.8 | 0.026 | 10 | 1.3 | 7 | 1.8 | -0.036 |
Sex | ||||||||||
Female | 677 | 57.0 | 258 | 62.1 | -0.103 | 459 | 61.3 | 243 | 61.8 | -0.011 |
Household income | ||||||||||
Low | 217 | 18.3 | 86 | 21.2 | -0.073 | 155 | 20.7 | 82 | 20.9 | -0.004 |
Middle | 294 | 24.8 | 110 | 26.9 | -0.049 | 213 | 28.4 | 107 | 27.2 | 0.027 |
High | 676 | 57.0 | 220 | 51.9 | 0.102 | 381 | 50.9 | 204 | 51.9 | -0.021 |
Charlson comorbidity index score | ||||||||||
0 | 442 | 37.2 | 153 | 36.7 | 0.012 | 277 | 37.0 | 144 | 36.6 | 0.007 |
1 | 398 | 33.5 | 142 | 34.4 | -0.019 | 258 | 34.5 | 135 | 34.4 | 0.002 |
2 | 212 | 17.9 | 75 | 18.0 | -0.003 | 127 | 17.0 | 71 | 18.1 | -0.029 |
≥ 3 | 135 | 11.4 | 46 | 11.0 | 0.013 | 87 | 11.6 | 43 | 10.9 | 0.021 |
Obesity | 462 | 38.9 | 163 | 40.7 | -0.035 | 307 | 41.0 | 159 | 40.5 | 0.011 |
Lab test gap (day), Mean (SD) | 725.6 | 182.3 | 764.2 | 189.9 | -0.207 | 739.1 | 181.1 | 759.7 | 193.3 | -0.110 |
1st LDL-C (mg/dL), Mean (SD) | 80.3 | 20.7 | 81.0 | 21.8 | -0.034 | 80.9 | 21.1 | 80.9 | 20.6 | 0.003 |
Co-medication | ||||||||||
Cardiovascular & endocrine | 162 | 13.7 | 52 | 13.0 | 0.020 | 100 | 13.4 | 50 | 12.7 | 0.019 |
Steroid & hormones | 323 | 27.2 | 118 | 29.4 | -0.049 | 202 | 27.0 | 118 | 30.0 | -0.068 |
Comorbidity | ||||||||||
Ischemic cardiovascular disease | 165 | 13.9 | 40 | 10.0 | 0.121 | 65 | 8.7 | 38 | 9.7 | -0.034 |
Stroke | 120 | 10.1 | 27 | 6.7 | 0.122 | 48 | 6.4 | 25 | 6.4 | 0.002 |
Arteriosclerosis | 6 | 0.5 | 1 | 0.3 | 0.042 | 1 | 0.1 | 1 | 0.3 | -0.028 |
Hypertension | 719 | 60.6 | 276 | 68.8 | -0.173 | 466 | 62.2 | 272 | 69.2 | -0.148 |
Diabetes mellitus | 308 | 26.0 | 102 | 25.4 | 0.012 | 207 | 27.6 | 100 | 25.4 | 0.050 |
Congestive heart failure | 10 | 0.8 | 2 | 0.5 | 0.044 | 7 | 0.9 | 2 | 0.5 | 0.050 |