Table 2 Multivariable logistic regression analysis of factors for switching

Age

 < 65

1.02

(0.37–2.79)

 70–74

reference

 75–80

0.92

(0.67–1.27)

 80–84

1.10

(0.73–1.67)

 ≥ 85

1.39

(0.48–4.05)

Sex

 Female

0.93

(0.71–1.23)

Income

 Low

reference

 Middle

0.97

(0.66–1.43)

 High

1.05

(0.74–1.48)

Obesity

 Yes

0.96

(0.73–1.26)

Charlson comorbidity index score

 0

reference

 1

1.17

(0.84–1.64)

 2

1.36

(0.89–2.08)

 ≥ 3

1.47

(0.85–2.57)

1st period medication

 Generic

reference

 Original

0.31

(0.20–0.48)

Switching medical institution

 Yes

6.83

(4.66–10.02)

1st period medical institution

 Hospital

reference

 Clinic

0.91

(0.65–1.29)

Co-medication

 Cardiovascular & endocrine

0.86

(0.58–1.29)

 Steroid & hormones

1.12

(0.84–1.51)

Comorbidity

 Hypertension

1.09

(0.80–1.49)

 Diabetes mellitus

0.69

(0.47–1.01)