Table 4 Comparison of differences in low-density lipoprotein-cholesterol levels in subgroups of switch patterns
Outcomes | Mean value | (95% CI) |
|---|---|---|
Non-switcher (n = 749) | ||
Original (n = 189) | ||
1st LDL-C, mg/dL | 76.10 | (74.47, 81.17) |
v2nd LDL-C, mg/dL | 76.26 | (73.08, 79.78) |
Mean difference, mg/dL | 0.15 | (-4.81, 2.03) |
Generic (n = 560) | ||
1st LDL-C, mg/dL | 83.56 | (80.16, 83.78) |
2nd LDL-C, mg/dL | 82.82 | (81.61, 85.22) |
Mean difference, mg/dL | -0.74 | (-0.42, 3.31) |
Switcher (n = 393) | ||
Original → Generic (n = 50) | ||
1st LDL-C, mg/dL | 78.96 | (82.44, 83.68) |
2nd LDL-C, mg/dL | 79.94 | (74.48, 85.72) |
Mean difference, mg/dL | 0.98 | (-3.15, 7.23) |
Generic → Original (n = 40) | ||
1st LDL-C, mg/dL | 83.56 | (74.60, 88.35) |
2nd LDL-C, mg/dL | 76.00 | (68.53, 82.27) |
Mean difference, mg/dL | -7.56 | (-12.34, 0.19) |
Generic → Another generic (n = 303) | ||
1st LDL-C, mg/dL | 83.56 | (78.64, 83.83) |
2nd LDL-C, mg/dL | 84.56 | (79.70, 84.90) |
Mean difference, mg/dL | 1.07 | (-1.34, 3.47) |