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Table 4 The study participants’ genotypes and the allele frequency distribution of the SNPs rs737337 and rs2278426

From: Genetic predisposition to nonalcoholic fatty liver disease: insights from ANGPTL8 gene variants in Iranian adults

SNP

Parameters

Allele

Groups

P Value

OR

NAFLD

Control

Rs737337

TT

0

67 (30.20)

94 (46.80)

< 0.001

2.032 (1.364–3.028)

1

155 (69.80)

107 (53.20)

TC

0

171 (77.00)

133 (66.20)

0.013

0.583 (0.380–0.895)

1

51 (23.00)

68 (33.80)

CC

0

206 (92.80)

175 (87.10)

0.049

0.523 (0.272–1.006)

1

16 (7.20)

26 (12.90)

rs2278426

CC

0

58 (26.10)

34 (16.90)

0.022

0.576 (0.358–0.926)

1

164 (73.90)

167 (83.10)

CT

0

170 (76.60)

173 (86.10)

0.013

1.890 (1.140–3.134)

1

52 (23.40)

28 (13.90)

TT

0

216 (97.30)

195 (97.00)

0.861

0.903 (0.286–2.846)

1

6 (2.70)

6 (3.00)