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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Anlotinib affects systemic lipid metabolism and induces lipid accumulation in human lung cancer cells

Fig. 2

Anlotinib treatment regulates key genes and enzymes required for cholesterol synthesis and uptake in the liver. A LDLR, SREBP1, SREBP2, HMGCR, AMPK, mTOR, ACC, SCD1 and FASN mRNA expression levels in the liver. B LDLR, HMGCR, p-AMPK, AMPK, p-mTOR and mTOR protein expression levels in the liver. C Corresponding histograms for protein expression levels. *P < 0.05; **P < 0.01 by Student’s t test

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