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Table 2 Association between RC and hypertension, T2DM, and their coexistence in NHANES 2005–2018 (N = 17,749)

From: Association of remnant cholesterol with hypertension, type 2 diabetes, and their coexistence: the mediating role of inflammation-related indicators

 

Unadjusted

Adjusted Model 1

Adjusted Model 2

Adjusted Model 3

 

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

OR (95% CI)

P value

Raw data with missing values

 Hypertension

3.829(3.321,4.415)

 < 0.001

2.601(2.252,3.004)

 < 0.001

2.697(2.317,3.139)

 < 0.001

1.068(1.063,1.073)

 < 0.001

 T2DM

4.158(3.603,4.798)

 < 0.001

3.342(2.817,3.964)

 < 0.001

3.557(2.950,4.288)

 < 0.001

2.259(1.797,2.838)

 < 0.001

 Hypertension &T2DM

4.107(3.478,4.849)

 < 0.001

3.449(2.821,4.217)

 < 0.001

3.787(3.045,4.710)

 < 0.001

2.362(1.834,3.041)

 < 0.001

Multiple Imputation based on mice

 Hypertension

3.829(3.321,4.415)

 < 0.001

2.601(2.252,3.004)

 < 0.001

2.914(2.526,3.362)

 < 0.001

1.866(1.594,2.186)

 < 0.001

 T2DM

4.158(3.603,4.798)

 < 0.001

3.342(2.817,3.964)

 < 0.001

3.594(3.002,4.304)

 < 0.001

2.466(2.030,2.996)

 < 0.001

 Hypertension & T2DM

4.107(3.478,4.849)

 < 0.001

3.449(2.821,4.217)

 < 0.001

3.900(3.171,4.797)

 < 0.001

2.661(2.148,3.297)

 < 0.001

Unit replaced with mg/dL

 Hypertension

1.035(1.032,1.039)

 < 0.001

1.025(1.021,1.029)

 < 0.001

1.026(1.022,1.030)

 < 0.001

1.014(1.010,1.019)

 < 0.001

 T2DM

1.038(1.034,1.041)

 < 0.001

1.032(1.027,1.036)

 < 0.001

1.033(1.028,1.038)

 < 0.001

1.021(1.015,1.027)

 < 0.001

 Hypertension & T2DM

1.037(1.033,1.042)

 < 0.001

1.033(1.027,1.038)

 < 0.001

1.035(1.029,1.041)

 < 0.001

1.022(1.016,1.029)

 < 0.001

  1. Notes: Model 1 was adjusted by age and sex; Model 2 was adjusted by age, sex, race, education, marital status, and PIR; Model 3 was additionally adjusted by smoking, alcohol, BMI levels, HEI, DII, and waist
  2. Abbreviations: T2DM Type 2 diabetes, RC Remnant cholesterol, OR Odds ratio, CI Confidence interval