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Table 4 Subgroup analysis of TFAs on ACR in the prespecified and exploratory subgroup

From: Positive associations between different circulating trans fatty acids (TFAs) and urinary albumin excretion among adults in the U.S.: a population-based study

 

Palmitelaidic acid

Elaidic acid

Linolelaidic acid

Sum TFAs

Stratified by Age

    

 < 60

0.30 (-0.38, 0.97) 0.390

0.38 (-0.12, 0.88) 0.136

0.44 (-0.24, 1.11) 0.204

0.20 (-0.36, 0.76) 0.486

 ≥ 60

0.96 (-0.54, 2.45) 0.211

1.39 (0.23, 2.56) 0.019

1.64 (0.04, 3.24) 0.044

1.44 (0.14, 2.74) 0.031

P for interaction

0.186

0.035

0.123

0.023

Stratified by BMI

    

 < 25

0.32 (-0.75, 1.39) 0.555

0.66 (-0.16, 1.49) 0.116

0.77 (-0.43, 1.98) 0.210

0.69 (-0.21, 1.60) 0.135

 25–30

0.43 (-0.68, 1.55) 0.449

0.53 (-0.31, 1.37) 0.214

0.72 (-0.38, 1.81) 0.199

0.29 (-0.65, 1.23) 0.543

 > 30

0.74 (-0.56, 2.04) 0.267

0.65 (-0.34, 1.64) 0.196

0.78 (-0.52, 2.09) 0.238

0.60 (-0.50, 1.71) 0.285

P for interaction

0.382

0.478

0.488

0.473

Stratified by eGFR

    

 < 60

1.69 (-4.81, 8.19) 0.612

0.83 (-4.56, 6.23) 0.763

2.00 (0.40, 3.60) 0.015

1.79 (0.47, 3.11) 0.008

 ≥ 60

0.07 (-0.58, 0.73) 0.826

0.09 (-0.41, 0.60) 0.720

0.12 (-0.56, 0.80) 0.736

-0.08 (-0.65, 0.48) 0.767

P for interaction

0.143

0.069

0.042

0.033

Hypertension

    

 Yes

1.62 (0.06, 3.18) 0.042

1.71 (0.53, 2.90) 0.005

2.00 (0.40, 3.60) 0.015

1.79 (0.47, 3.11) 0.008

 No

-0.09 (-0.74, 0.57) 0.797

0.09 (-0.41, 0.60) 0.720

0.12 (-0.56, 0.80) 0.736

-0.08 (-0.65, 0.48) 0.767

P for interaction

0.007

0.005

0.013

0.003

Diabetes

    

 Yes

-3.15 (-6.60, 0.30) 0.075

-0.83 (-3.39, 1.73) 0.526

-0.97 (-4.54, 2.60) 0.595

-1.64 (-4.45, 1.18) 0.255

 No

0.80 (0.13, 1.46) 0.019

0.80 (0.30, 1.30) 0.002

0.78 (0.10, 1.46) 0.025

0.78 (0.22, 1.34) 0.007

Border line

5.95 (-2.17, 14.07) 0.165

0.37 (-5.74, 6.49) 0.905

4.67 (-3.60, 12.95) 0.280

1.48 (-5.30, 8.27) 0.673

P for interaction

< 0.001

0.004

0.003

< 0.001

NAFLD

    

 Yes

0.39 (-1.66, 2.44) 0.709

0.93 (-0.62, 2.47) 0.241

0.99 (-1.22, 3.19) 0.380

0.82 (-0.95, 2.59) 0.362

 No

0.69 (-0.02, 1.39) 0.057

0.71 (0.17, 1.24) 0.009

0.82 (0.11, 1.54) 0.024

0.65 (0.06, 1.24) 0.032

P for interaction

0.596

0.853

0.844

0.832

Coronary heart disease

    

 Yes

-1.96 (-7.76, 3.84) 0.510

2.09 (-2.58, 6.76) 0.383

4.88 (-1.61, 11.38) 0.144

1.42 (-3.86, 6.70) 0.599

 No

0.76 (0.09, 1.43) 0.025

0.74 (0.23, 1.24) 0.004

0.77 (0.09, 1.45) 0.026

0.69 (0.13, 1.25) 0.016

P for interaction

0.065

0.486

0.832

0.283

  1. Note1: Model 3: Fully adjusted model was adjusted by age, gender, race/ethnicity, education level, poverty income ratio, ALT, AST, SCr, total cholesterol, triglycerides, LDL-C, HDL-C, serum uric acid, albumin, glycohemoglobin, eGFR, BMI, SBP, DBP, waist circumference, physical activity (MET-based rank), current cigarette use, now taking prescribed medicine for HBP, now taking prescribed medicine for high cholesterol level, had at least 12 alcohol drinks/1 year, hypertension history, NAFLD, diabetes history, coronary heart disease. Note2: In each case, the model was not adjusted for the stratification variable itself. Bold values mean statistically significant
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Lipids in Health and Disease

ISSN: 1476-511X