Positive associations between different circulating trans fatty acids (TFAs) and urinary albumin excretion among adults in the U.S.: a population-based study

Table 5 Threshold effect analysis of TFAs on ACR using a two-piecewise linear regression model

Exposure:	Palmitelaidic acid	Vaccenic acid	Elaidic acid	Linolelaidic acid	Sum TFAs
two-piecewise linear model
Break point (K)	11.2	10.6	59.1	4.79	137.86
β1(95% CI), <K P-value	0.26 (0.07, 0.46) 0.0067	-0.43 (-0.91, 0.05) 0.0804	0.06 (0.03, 0.09) 0.0003	0.62 (0.16, 1.08) 0.0089	0.02 (0.01, 0.04) 0.0027
β2(95% CI), >K P-value	-0.15 (-0.55, 0.25) 0.4659	0.03 (0.00, 0.05) 0.0194	-0.03 (-0.08, 0.03) 0.3859	-0.29 (-1.19, 0.61) 0.5335	-0.00 (-0.03, 0.02) 0.7112
β2-β1	-0.41 (-0.89, 0.06) 0.0881	0.45 (-0.03, 0.94) 0.0650	-0.09 (-0.16, -0.01) 0.0208	-0.90 (-1.96, 0.16) 0.0946	-0.03 (-0.06, 0.00) 0.0859
logarithmic likelihood ratio test P-value	0.086	0.064	0.020	0.093	0.084

Fully adjusted model was adjusted by age, gender, race/ethnicity, education level, poverty income ratio, ALT, AST, SCr, total cholesterol, triglycerides, LDL-C, HDL-C, serum uric acid, albumin, glycohemoglobin, eGFR, BMI, SBP, DBP, waist circumference, physical activity (MET-based rank), current cigarette use, now taking prescribed medicine for HBP, now taking prescribed medicine for high cholesterol level had at least 12 alcohol drinks/1 year, smoked at least 100 cigarettes in life, hypertension history, NAFLD, diabetes history, coronary heart disease

ISSN: 1476-511X