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Fig. 6 | Lipids in Health and Disease

Fig. 6

From: Identification of key lipid metabolism-related genes in Alzheimer’s disease

Fig. 6

The three key DELMRGs expression levels in internal and external AD datasets. Gene expression was normalized to the raw expression matrix using the z-score method. (A) – (C) In frontal cortex samples of the GSE122063 dataset, DLD was down-regulated and PLAAT4 and PLPP2 exhibited upregulation in AD compared to controls. (D) – (F) In temporal cortex samples of the GSE122063 dataset, DLD was down-regulated and PLAAT4 and PLPP2 exhibited upregulation in AD compared to controls. (G) – (I) In the GSE132903 dataset, DLD was down-regulated and PLAAT4 and PLPP2 exhibited upregulation in AD compared to controls. (J) - (L) In the GSE33000 dataset, DLD was down-regulated and PLAAT4 and PLPP2 exhibited upregulation in AD compared to controls

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