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Table 3 Ceramide change following liraglutide

From: Ceramides are decreased after liraglutide treatment in people with type 2 diabetes: a post hoc analysis of two randomized clinical trials

 

LirAlbu12

LiraFlame26

 

Estimated ceramide change

Standard Error

P-value

Estimated ceramide change

Standard Error

P-value

C16 Cer

-0.033

0.028

0.240

-2.556*10–4

1.260*10–4

0.045*

C18 Cer

-0.015

0.033

0.639

-6.000*10–4

3.459*10–4

0.086

C20 Cer

-0.031

0.053

0.559

2.953*10–5

2.629*10–5

0.264

C22 Cer

-0.239

0.252

0.344

-1.272*10–4

1.690*10–4

0.454

C24 Cer

-1.006

1.075

0.352

-3.108*10–2

1.929*10–2

0.110

C24:1 Cer

0.089

0.326

0.786

-1.342*10–2

6.680*10–3

0.047*

  1. Linear mixed models were constructed for each ceramide in both trials with the following formula:
  2. \(Ceramide\:\sim\:Treatment\:+Time+Treatment:Time+(1\vert Participant\;ID)\) 
  3. * Indicate P-value < 0.05
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Lipids in Health and Disease

ISSN: 1476-511X