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Fig. 2 | Lipids in Health and Disease

Fig. 2

From: Rotundic acid improves nonalcoholic steatohepatitis in mice by regulating glycolysis and the TLR4/AP1 signaling pathway

Fig. 2

An overview of transcriptome and functional enrichment analysis of DEGs. A-B Global gene expression changes of M vs. C (A) and RA vs. M (B) are plotted as volcano plots. DEGs in red are upregulated, DEGs in green are downregulated, and non-DEGs are highlighted in gray. C Venn diagram of intersecting DEGs of M vs. C and RA vs. M. D-E Top 10 categories for GO biological processes (D) and KEGG pathways (E) of DEGs depicted by bubble diagrams. The color indicates the Q value, and the size indicates the gene number of each pathway. C: Control group. M: NASH group. RA: RA-30 group. N = 10 per group

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