Combination of the glycated hemoglobin levels and prognostic nutritional index as a prognostic marker in patients with acute coronary syndrome and type 2 diabetes mellitus

Table 2 Cox proportional hazard models for MACCE and all-cause mortality

Groups	Model 1		Model 2		Model 3		Model 4
MACCE	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P	HR (95%CI)	P
H-PNI/L-HbA1c	1.00 (reference)	/	1.00 (reference)	/	1.00 (reference)	/	1.00 (reference)	/
H-PNI/H-HbA1c	1.59(0.71–3.53)	0.259	1.59(0.71–3.53)	0.258	1.52(0.68–3.39)	0.307	1.51(0.68–3.39)	0.313
L-PNI/ L-HbA1c	2.00(0.93–4.29)	0.077	1.82(0.84–3.95)	0.128	1.56(0.71–3.39)	0.265	1.60(0.73–3.48)	0.239
L-PNI/H-HbA1c	2.94(1.44–6.04)	0.003	2.80(1.36–5.77)	0.005	2.47(1.18–5.14)	0.016	2.50(1.20–5.23)	0.014
All-cause mortality
H-PNI/L-HbA1c	1.00 (reference)	/	1.00 (reference)	/	1.00 (reference)	/	1.00 (reference)	/
H-PNI/H-HbA1c	1.32(0.35–4.90)	0.682	1.31(0.35–4.88)	0.687	1.26(0.34–4.71)	0.731	1.29(0.34–4.84)	0.708
L-PNI/ L-HbA1c	2.89(0.92–9.07)	0.069	2.48(0.78–7.86)	0.123	2.03(0.64–6.48)	0.231	2.06(0.64–6.58)	0.223
L-PNI/H-HbA1c	4.05(1.35–12.10)	0.012	3.67(1.22–11.05)	0.02	3.14(1.03–9.60)	0.044	3.20(1.04–9.82)	0.042

Data are presented as HR (hazard ratio), 95% CI (confidence intervals), and P-value
Model 1: unadjusted
Model 2: adjusted for Age, Sex, BMI, and Current smoker
Model 3: adjusted for Age, Sex, BMI, Current smoker, Hypertension, Hyperlipidemia, Prior MI, HF, CKD, ACS type
Model 4: adjusted for Age, Sex, BMI, Current smoker, Hypertension, Hyperlipidemia, Prior MI, HF, CKD, ACS type, TG, TC, LDL-C

ISSN: 1476-511X