Table 2 Characteristics of the pregnant women with SCH in the first trimester
|  | Total (n = 952) | SCH without dyslipidemia (n = 770) | SCH with dyslipidemia (n = 182) | P-value |
|---|---|---|---|---|
Maternal Age (year) | 31.00(28.00, 33.00) | 30.00(28.00, 33.00) | 32.00(29.00, 34.25) | ＜0.001* |
 < 35 | 777(81.62) | 640(83.12) | 137(75.27) | 0.014* |
 ≥ 35 | 175(18.38) | 130(16.88) | 45(24.73) |  |
Pre-pregnancy BMI (kg/m2) | 21.09(19.49, 23.70) | 20.76(19.22, 23.05) | 23.03(20.56, 26.01) | ＜0.001* |
 < 24 | 738(77.52) | 630(81.82) | 108(59.34) | 0.000* |
 24–28 | 157(16.49) | 110(14.29) | 47(25.82) |  |
 ≥ 28 | 57(5.99) | 30(3.90) | 27(14.84) |  |
 Smoking (Yes) | 3(0.32) | 1(0.14) | 2(1.20) | 0.092 |
 Drinking (Yes) | 42(4.41) | 36(4.68) | 6(3.30) | 0.415 |
 Education level |  |  |  | 0.250 |
 < College | 69(7.25) | 51(7.03) | 18(10.78) |  |
 Undergraduate/College | 621(65.23) | 507(69.93) | 114(68.26) |  |
 >Postgraduate/higher | 202(21.22) | 167(23.03) | 35(20.96) |  |
 TSH (mIU/L) | 4.89(4.34, 5.75) | 4.89(4.34, 5.74) | 4.90(4.35, 5.77) | 0.630 |
 FT4 (pmol/L) | 14.72(13.82, 15.81) | 14.70(13.80, 15.74) | 14.75(13.99, 16.07) | 0.168 |
 TC (mmol/L) | 4.22(3.76, 4.70) | 4.13(3.74, 4.54) | 5.04(4.01, 5.55) | ＜0.001* |
 TG (mmol/L) | 0.99(0.78, 1.35) | 0.92(0.73, 1.19) | 1.67(1.21, 2.24) | ＜0.001* |
 LDL-C (mmol/L) | 2.19(1.84, 2.64) | 2.12(1.81, 2.48) | 2.87(2.12, 3.40) | ＜0.001* |
 HDL-C (mmol/L) | 1.49(1.28, 1.72) | 1.52(1.33, 1.73) | 1.33(1.05, 1.68) | ＜0.001* |
 Vaginal delivery | 570(59.87) | 465(60.39) | 105(57.69) | 0.505 |
 Cesarean Section | 333(34.98) | 265(34.42) | 68(37.36) | 0.454 |
 Pregnancy loss | 49(5.15) | 40(5.19) | 9(4.95) | 0.891 |
 Gestational hypertension | 37(3.89) | 25(3.25) | 12(6.59) | 0.036* |
 Preeclampsia/Eclampsia | 37(3.89) | 24(3.12) | 13(7.14) | 0.012* |
 GDM | 147(15.44) | 106(13.77) | 41(22.53) | 0.003* |
 PROM | 279(29.31) | 227(29.48) | 52(28.57) | 0.809 |
 FGR | 93(9.77) | 72(9.35) | 21(11.54) | 0.372 |
 Preterm birth | 32(3.36) | 23(2.99) | 9(4.95) | 0.188 |
 Low birth weight | 25(2.63) | 16(2.08) | 9(4.95) | 0.030* |
 Macrosomia | 59(6.20) | 46(5.97) | 13(7.14) | 0.557 |
 Birth defects | 37(3.89) | 31(4.03) | 6(3.30) | 0.647 |