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Table 3 Odds ratios of adverse outcomes in SCH with dyslipidemia compared with those without dyslipidemia

From: The association between dyslipidaemia in the first trimester and adverse pregnancy outcomes in pregnant women with subclinical hypothyroidism: a cohort study

Maternal and neonatal outcomes

 

Without dyslipidemia

 

Dyslipidemia

 

Dyslipidemia

   

Crude

P-values

 

Adjusted

P-values

Vaginal delivery

 

reference

 

0.894 (0.645–1.241)

0.504

 

1.238 (0.858–1.785)

0.253

Caesarean Section

 

reference

 

1.137 (0.813–1.589)

0.454

 

0.851 (0.586–1.236)

0.396

Pregnancy loss

 

reference

 

0.949 (0.452–1.994)

0.891

 

0.783 (0.345–1.773)

0.557

Gestational hypertension

 

reference

 

2.104 (1.036–4.271)

0.040*

 

1.996 (0.913–4.364)

0.083

Preeclampsia/Eclampsia

 

reference

 

2.391 (1.193–4.792)

0.014*

 

1.557 (0.680–3.568)

0.295

GDM

 

reference

 

1.821 (1.216–2.727)

0.004*

 

1.427 (0.911–2.325)

0.121

PROM

 

reference

 

0.957 (0.670–1.367)

0.809

 

1.009 (0.684–1.490)

0.964

FGR

 

reference

 

1.264 (0.755–2.117)

0.372

 

1.293 (0.733–2.282)

0.375

Preterm birth

 

reference

 

1.690 (0.768–3.716)

0.192

 

1.308 (0.550–3.114)

0.543

Low birth weight

 

reference

 

2.452 (1.066–5.640)

0.035*

 

1.923 (0.744–4.976)

0.177

Macrosomia

 

reference

 

1.211 (0.640–2.291)

0.557

 

0.632 (0.269–1.483)

0.291

Birth defects

 

reference

 

0.813 (0.334–1.978)

0.648

 

0.837 (0.333–2.107)

0.706

  1. Abbreviations: SCH subclinical hypothyroidism; BMI body mass index; GDM gestational diabetes mellitus; PROM, premature rupture of fetal membranes; FGR fetal growth restriction; L-T4 levothyroxine
  2. Crude: No adjustment. Adjusted: L-T4 use, age, alcohol use, smoking, and pre-BMI.
  3. *P-values < 0.05 was considered statistically significant