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Table 4 Multivariable regression results for several adverse pregnancy outcomes

From: The association between dyslipidaemia in the first trimester and adverse pregnancy outcomes in pregnant women with subclinical hypothyroidism: a cohort study

Maternal and neonatal outcomes

Without dyslipidemia

 

Dyslipidemia

  

OR (95%CI)

P-values

Gestational hypertension

    

 Model 1

reference

 

2.171 (1.066–4.421)

0.033*

 Model 2

reference

 

2.092 (1.017–4.301)

0.045*

 Model 3

reference

 

2.810 (1.321–5.975)

0.007*

 Model 4

reference

 

1.996 (0.913–4.364)

0.083

Preeclampsia/Eclampsia

    

 Model 1

reference

 

2.400 (1.197–4.813)

0.014*

 Model 2

reference

 

2.366 (1.171–4.777)

0.016*

 Model 3

reference

 

1.878 (0.835–4.225)

0.128

 Model 4

reference

 

1.557 (0.680–3.568)

0.295

GDM

    

 Model 1

reference

 

1.870 (1.245–2.809)

0.003*

 Model 2

reference

 

1.609 (1.059–2.446)

0.026*

 Model 3

reference

 

1.702 (1.101–2.632)

0.017*

 Model 4

reference

 

1.427 (0.911–2.325)

0.121

Low birth weight

    

 Model 1

reference

 

2.462 (1.070–5.668)

0.034*

 Model 2

reference

 

2.422 (1.043–5.624)

0.040*

 Model 3

reference

 

2.114 (0.838–5.332)

0.113

 Model 4

reference

 

1.923 (0.744–4.976)

0.177

  1. Abbreviations: GDM gestational diabetes mellitus; BMI body mass index; L-T4 levothyroxine
  2. Model 1: Adjusted for L-T4 use
  3. Model 2: Adjusted for the same variables as Model 1 as well as age
  4. Model 3: Adjusted for the same variables as Model 2 as well as d alcohol use and smoking
  5. Model 4: Adjusted for the same variables as Model 3 as well as pre-BMI.
  6. *P-values < 0.05 was considered statistically significant